Comparison of Three-Year Clinical Outcomes Between Sirolimus-Versus Paclitaxel-Eluting Stents in Diabetic Patients: Prospective Randomized Multicenter Trial
- Authors
- Hong, SJ[Hong, Soon Jun]; Kim, MH[Kim, Moo Hyun]; Cha, KS[Cha, Kwang Soo]; Park, HS[Park, Hun Sik]; Chae, SC[Chae, Shung Chull]; Hur, SH[Hur, Seung Ho]; Gwon, HC[Gwon, Hyeon Cheol]; Bae, JH[Bae, Jang Ho]; Lim, DS[Lim, Do-Sun]
- Issue Date
- 1-Dec-2010
- Publisher
- WILEY-LISS
- Keywords
- drug-eluting stents; diabetes mellitus; survival analysis; major adverse cardiac event; stent thrombosis
- Citation
- CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, v.76, no.7, pp.924 - 933
- Indexed
- SCIE
SCOPUS
- Journal Title
- CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
- Volume
- 76
- Number
- 7
- Start Page
- 924
- End Page
- 933
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/72579
- DOI
- 10.1002/ccd.22369
- ISSN
- 1522-1946
- Abstract
- Background: Three-year follow-up of major adverse cardiovascular event (MACE) (death, nonfatal myocardial infarction, target lesion revascularization) and the predictors of MACEs in diabetic patients after sirolimus-eluting stent (SES) or paclitaxel-eluting stent (PES) implantation have not been reported. Methods: Diabetic patients with de novo coronary lesions (169 patients with 190 lesions) were randomly assigned prospectively to either SES or PES. Results: Baseline characteristics were similar between the two groups. The rates of MACEs [5.9% (n = 5) in the SES vs. 9.5% (n = 8) in the PES Group, P = 0.374] and definite stent thrombosis [1.2% (n = 1) in the SES vs. 3.6% (n = 3) in the PES Group, P = 0.368] were similar in the two groups during the three-year follow-up. Multivariate logistic analysis showed that insulin treatment was the only independent predictor of MACE [odds ratio (OR) 8.60, 95% confidence interval (CI) 3.25-22.76, P < 0.001] and target vessel revascularization (TVR) (OR 9.50, 95% CI 3.07-29.44, P < 0.001) during the three-year follow-up. Conclusions: The rates of MACEs, TVR, and stent thrombosis during the three-year follow-up were similar in the SES and PES Groups. Insulin treatment was a main predictor of MACEs and TVR during the three-year follow-up after either SES or PES implantation. (C) 2010 Wiley-Liss, Inc.
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Collections - Medicine > Department of Medicine > 1. Journal Articles
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