Polypyrrole nanowire modified with Gly-Gly-His tripeptide for electrochemical detection of copper ion
- Authors
- Lin, M[Lin, Meng]; Cho, M[Cho, MiSuk]; Choe, WS[Choe, Woo-Seok]; Yoo, JB[Yoo, Ji-Beom]; Lee, Y[Lee, Youngkwan]
- Issue Date
- 15-Oct-2010
- Publisher
- ELSEVIER ADVANCED TECHNOLOGY
- Keywords
- Overoxidized polypyrrole; Nanowire; Peptide; Copper ion; Biosensor; Electrochemical analysis
- Citation
- BIOSENSORS & BIOELECTRONICS, v.26, no.2, pp.940 - 945
- Indexed
- SCIE
SCOPUS
- Journal Title
- BIOSENSORS & BIOELECTRONICS
- Volume
- 26
- Number
- 2
- Start Page
- 940
- End Page
- 945
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/73093
- DOI
- 10.1016/j.bios.2010.06.030
- ISSN
- 0956-5663
- Abstract
- We developed a novel biosensor comprising a transducer of carboxyl end-capped overoxidized polypyrrole nanowire electrode and a probe of tripeptide (Gly-Gly-His) selectively cognitive of Cu(2+). The developed sensor was demonstrated to specifically detect Cu(2+) in the nanomolar range. The diameter of the polypyrrole nanowires, prepared by one step template-free polymerization, was approximately 60-90 nm. For functionalization of the electrode, the carboxyl group was introduced by the addition of pyrrole-alpha-carboxylic acid which was covalently coupled with the amine group of the tripeptide. The structural features of the peptide functionalized nanowire electrode were confirmed by X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM) spectroscopy. Using cyclic and square wave voltammetry, the nanowire biosensor proved to be highly sensitive to Cu(2+) in the range of 20-300 nM. (c) 2010 Elsevier B.V. All rights reserved.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - Engineering > School of Advanced Materials Science and Engineering > 1. Journal Articles
- Engineering > School of Chemical Engineering > 1. Journal Articles
- Engineering > Chemical Engineering > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/73093)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.