Incidental Detection of Ductal Carcinoma In Situ of the Breast from Bilateral Prophylactic Mastectomy of Asymptomatic BRCA2 Mutation Carrier: A Case Reportopen access
- Authors
- Choi, MY[Choi, Min-Young]; Lee, JE[Lee, Jeong Eon]; Kim, SW[Kim, Sung-Won]; Lee, SK[Lee, Se Kyung]; Hur, SM[Hur, Sung Mo]; Kim, S[Kim, Sangmin]; Koo, MY[Koo, Min Young]; Bae, SY[Bae, Soo Youn]; Choe, JH[Choe, Jun-Ho]; Kim, JH[Kim, Jung-Han]; Kim, JS[Kim, Jee Soo]; Nam, SJ[Nam, Seok Jin]; Yang, JH[Yang, Jung-Hyun]
- Issue Date
- Sep-2010
- Publisher
- KOREAN BREAST CANCER SOC
- Keywords
- Bilateral mastectomy; BRCA2 gene mutation; Breast neoplasms; Hereditary; Prevention
- Citation
- JOURNAL OF BREAST CANCER, v.13, no.3, pp.311 - 317
- Indexed
- SCIE
SCOPUS
KCI
OTHER
- Journal Title
- JOURNAL OF BREAST CANCER
- Volume
- 13
- Number
- 3
- Start Page
- 311
- End Page
- 317
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/73440
- DOI
- 10.4048/jbc.2010.13.3.311
- ISSN
- 1738-6756
- Abstract
- In women at high-risk for breast cancer with a BRCA mutation, bilateral prophylactic mastectomy (BPM) may achieve a risk reduction. A 35-year-old woman had a strong family history of breast and ovarian cancer. She had a regular checkup and found masses in both breasts that confirmed intraductal papillomas and atypical ductal hyperplasia after vacuum assisted mass excision. When she was referred to our clinic, the genetic testing for BRCA mutation was recommended to her sister that managed for ovarian cancer. It was resulted in the positive for the BRCA2 mutation, so she had checked the genetic testing which resulted in the same as the mutation. After sufficient counseling, she decided to undergo BPM and immediate reconstruction. She is satisfied with the result of surgery. This is the first report of BPM of asymptomatic BRCA2 mutation carrier in Korea and BPM should be considered as a risk-reducing option for BRCA mutation carriers.
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Collections - Medicine > Department of Medicine > 1. Journal Articles
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