Prediction of Complete Necrosis of Hepatocellular Carcinoma Treated with Transarterial Chemoembolization Prior to Liver Transplantation
- Authors
- Kim, SJ[Kim, Sue Jin]; Choi, MS[Choi, Moon Seok]; Kang, JY[Kang, Ja Young]; Choi, DI[Choi, Dong Il]; Park, CK[Park, Cheol Keun]; Gwak, GY[Gwak, Geum Youn]; Lee, JH[Lee, Joon Hyoek]; Koh, KC[Koh, Kwang Cheol]; Paik, SW[Paik, Seung Woon]; Yoo, BC[Yoo, Byung Chul]
- Issue Date
- Dec-2009
- Publisher
- EDITORIAL OFFICE GUT & LIVER
- Citation
- GUT AND LIVER, v.3, no.4, pp.285 - 291
- Indexed
- SCIE
SCOPUS
KCI
OTHER
- Journal Title
- GUT AND LIVER
- Volume
- 3
- Number
- 4
- Start Page
- 285
- End Page
- 291
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/76470
- DOI
- 10.5009/gnl.2009.3.4.285
- ISSN
- 1976-2283
- Abstract
- Background/Aims: Compact lipiodol uptake without enhancement on multiphasic helical computed tomography (CT) has been suggested as a radiologic response criterion in hepatocellular carcinoma (HCC) patients treated with transarterial chemoembolization (TACE) and subsequent partial hepatectomy. However, its usefulness has not been fully investigated in the explanted liver. Methods: Between 1998 and 2007, 81 patients with HCC underwent 1-9 sessions of TACE followed by liver transplantation (LT). Thirty-nine tumors in 29 patients showed a radiologic response on CT performed prior to LT. The radiologic response criteria and the duration of the response were evaluated to predict total necrosis in the explanted liver. Results: Among the 39 tumors, 34 nodules (87.2%) exhibited total pathological necrosis. While 13 out of 16 tumors (81.3%) with a radiologic response for 6 months or less were completely necrotic, 21 out of 23 tumors (91.3%) with a radiologic response of longer than 6 months showed total necrosis. Conclusions: Our results suggested that the radiologic response criteria based on serial CT images might be useful for predicting total necrosis of TACE-pretreated HCC in LT. (Gut and Liver 2009;3:285-291)
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Collections - Medicine > Department of Medicine > 1. Journal Articles
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