Comparison of Two-Year Outcomes of Acute Myocardial Infarction Caused by Coronary Artery Spasm Versus that Caused by Coronary Atherosclerosis
- Authors
- Baek, JY[Baek, Ju Yeol]; Choi, BG[Choi, Byoung Geol]; Rha, SW[Rha, Seung-Woon]; Choi, CU[Choi, Cheol Ung]; Park, CG[Park, Chang Gyu]; Seo, HS[Seo, Hong Seog]; Oh, DJ[Oh, Dong Joo]; Ahn, TH[Ahn, Tae Hoon]; Chang, K[Chang, Kiyuk]; Chae, SC[Chae, Shung-Chull]; Hur, SH[Hur, Seung Ho]; Cha, KS[Cha, Kwang-Soo]; Choi, IH[Choi, In-Ho]; Kim, HS[Kim, Hyo-Soo]; Gwon, HC[Gwon, Hyeon Cheol]; Kim, YJ[Kim, Young Jo]; Oh, SK[Oh, Seok Kyu]; Chae, JK[Chae, Jei Keon]; Seong, IW[Seong, In Whan]; Hwang, KK[Hwang, Kyung-Kook]; Kim, CJ[Kim, Chong Jin]; Yoon, JH[Yoon, Jung-Han]; Hwang, JY[Hwang, Jin Yong]; Kim, DI[Kim, Doo Il]; Joo, SJ[Joo, Seung Jae]; Jeong, MH[Jeong, Myung Ho]
- Issue Date
- 15-Nov-2019
- Publisher
- EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
- Citation
- AMERICAN JOURNAL OF CARDIOLOGY, v.124, no.10, pp.1493 - 1500
- Indexed
- SCIE
SCOPUS
- Journal Title
- AMERICAN JOURNAL OF CARDIOLOGY
- Volume
- 124
- Number
- 10
- Start Page
- 1493
- End Page
- 1500
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/8101
- DOI
- 10.1016/j.amjcard.2019.08.019
- ISSN
- 0002-9149
- Abstract
- The study compared the 2-year outcomes of patients diagnosed with acute myocardial infarction (AMI) triggered by coronary artery atherosclerosis and AMI caused by coronary artery spasm. A total of 36,797 patients in the Korea AMI Registry were grouped into 2 categories-(1) AMI due to coronary artery spasm without stenotic lesion (CAS-AMI, n = 484); and (2) AMI induced by coronary artery atherosclerosis (CAA-AMI, n = 36,313). The major clinical outcomes of the 2 groups were compared over a 2-year clinical follow-up period. Major adverse cardiac events (MACE) were defined as the composite of total death, nonfatal myocardial infarction, and repeat revascularization. The incidence of MACE (7.1% vs 11.1%; p = 0.007) and repeat revascularization (0.4% vs 4.2 %; p <0.001) in the CAS-AMI group were significantly lower than in the CAA-AMI group at 2 years. However, the incidence of total death and nonfatal myocardial infarction was similar in both the groups. Aborted cardiac arrest was strongly associated with 2-year mortality in the CAS-AMI group (hazard ratios 13.5, 95% confidence interval 5.34 to 34.15, p <0.001) The incidence of MACE in CAS-AMI patients was significantly lower than in the CAA-AMI group of patients up to 2 years due to the relatively lower rate of repeat revascularization in CAS-AMI patients. However, the incidence of total death or nonfatal myocardial infarction in CAS-AMI patients was not different from that of patients with CAA-AMI. (C) 2019 Elsevier Inc. All rights reserved.
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Collections - Medicine > Department of Medicine > 1. Journal Articles
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