Coronary calcium screening using low-dose lung cancer screening: Effectiveness of MDCT with retrospective reconstruction
- Authors
- Kim, SM[Kim, Sung Mok]; Chung, MJ[Chung, Myung Jin]; Lee, KS[Lee, Kyung Soo]; Choe, YH[Choe, Yeon Hyun]; Yi, CA[Yi, Chin A.]; Choe, BK[Choe, Bong-Keun]
- Issue Date
- Apr-2008
- Publisher
- AMER ROENTGEN RAY SOC
- Keywords
- calcium-scoring CT; coronary artery calcium; lung cancer screening; MDCT; radiation dose; screening
- Citation
- AMERICAN JOURNAL OF ROENTGENOLOGY, v.190, no.4, pp.917 - 922
- Indexed
- SCIE
SCOPUS
- Journal Title
- AMERICAN JOURNAL OF ROENTGENOLOGY
- Volume
- 190
- Number
- 4
- Start Page
- 917
- End Page
- 922
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/81775
- DOI
- 10.2214/AJR.07.2979
- ISSN
- 0361-803X
- Abstract
- OBJECTIVE. The purpose of our study was to show the usefulness of nongated low-dose chest CT for coronary screening by comparing the results of coronary artery calcium measurement with that of dedicated calcium-scoring CT. MATERIALS AND METHODS. One hundred twenty-eight consecutive participants (all men; mean age, 52 +/- 7 years) underwent low-dose chest CT and calcium-scoring CT with prospective ECG gating using 40-MDCT. Low-dose chest CT volume data were reconstructed as 25-cm field of view and three slice thicknesses: 1, 2.5, and 5 mm. For each examination, the lesion area, Agatston calcium score, and calcium mass were measured at 90- and 130-H thresholds. All measurements (130-H threshold) from the calcium-scoring CT were used as reference standards. Spearman's correlation test was used to compare the results. RESULTS. Among the low-dose chest CT examinations, sensitivity was best determined with a 1-mm slice thickness at 130 H and 2.5-mm slice thickness at 90 H. Specificity was best determined with a 5-mm slice thickness at 130 H. Accuracy (90%) was best determined with a 2.5-mm slice thickness at 130 H. Of all protocols, calcium area, score, and mass from a 2.5-mm slice thickness at 130 H correlated best with the reference results (r = 0.89 for all three criteria). CONCLUSION. Using a low radiation dose and nongated MDCT, we can detect coronary artery calcium and obtain results comparable to those obtained with dedicated calcium-scoring CT that uses a higher dose and ECG gating.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - Medicine > Department of Medicine > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/81775)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.