Detailed Information
Cited 9 time in 
Cited 0 time in 
Cited 0 time in
Metadata Downloads
Linkage disequilibrium (LD) mapping and tagging SNP selection of c-fos induced growth factor (FigF) gene
- Authors
- Kim, S[Kim, Sook]; Yoo, YK[Yoo, Yeon-Kyung]; Jang, HY[Jang, Hye-Yoon]; Shin, ES[Shin, Eun-Soon]; Cho, EY[Cho, Eun-Young]; Kim, E[Kim, Eugene]; Namkung, J[Namkung, Junghyun]; Yang, JM[Yang, Jun-Mo]; Lee, JE[Lee, Jong-Eun]
- Issue Date
- 31-Mar-2006
- Publisher
- KOREAN SOC TOXICOGENOMICS & TOXICOPROTEOMICS
- Keywords
- SNP; FigF gene; haplotype; linkage disequilibrium
- Citation
- MOLECULAR & CELLULAR TOXICOLOGY, v.2, no.1, pp.7 - 10
- Indexed
- SCIE
- Journal Title
- MOLECULAR & CELLULAR TOXICOLOGY
- Volume
- 2
- Number
- 1
- Start Page
- 7
- End Page
- 10
- ISSN
- 1738-642X
- Abstract
- We performed comprehensive SNP validation and linkage disequilibrium (LD) analysis of the c-fos induced growth factor(Figf) gene in Korean population. Out of 32 SNPs, only 9 SNPs were polymorphic in Korean population. Validated SNPs formed a single extended haplotype block with strong LD through the entire length of the gene. Tagging SNP analysis picked only 2 SNPs to represent most of the genetic variation information of the Figf gene. Our results demonstrate the utility of LD block and tagging SNP analysis for an efficient way of performing a candidate gene based association study.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - Medicine > Department of Medicine > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.