Detailed Information
Cited 9 time in 
Cited 8 time in 
Cited 8 time in
Metadata Downloads
Synthesis of Cinnolines via Rh(III)-Catalyzed Annulation of N-Aryl Heterocycles with Vinylene Carbonate
- Authors
- Kim, S[Kim, Suho]; Choi, SB[Choi, Su Bin]; Kang, JY[Kang, Ju Young]; An, W[An, Won]; Lee, SH[Lee, Suk Hun]; Oh, H[Oh, Harin]; Ghosh, P[Ghosh, Prithwish]; Mishra, NK[Mishra, Neeraj Kumar]; Kim, IS[Kim, In Su]
- Issue Date
- Nov-2021
- Publisher
- WILEY-V C H VERLAG GMBH
- Keywords
- annulation; C-H functionalization; cinnoline; rhodium; vinylene carbonate
- Citation
- ASIAN JOURNAL OF ORGANIC CHEMISTRY, v.10, no.11, pp.3005 - 3014
- Indexed
- SCIE
SCOPUS
- Journal Title
- ASIAN JOURNAL OF ORGANIC CHEMISTRY
- Volume
- 10
- Number
- 11
- Start Page
- 3005
- End Page
- 3014
- ISSN
- 2193-5807
- Abstract
- The Rh(III)-catalyzed C-H annulation reactions of N-aryl indazolones or N-aryl phthalazinones with a vinylene carbonate is described herein. This transformation provides the rapid access to indazolocinnolines and phthalazinocinnolines as important assets towards the development of novel bioactive compounds. Intriguingly, a vinylene carbonate acts as a vinyl transfer agent to enable the [4+2] annulation reaction. This method is characterized by its simplicity, mild reaction conditions, and broad functional group tolerance.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - Pharmacy > Department of Pharmacy > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.