Histological Diagnostic Yield and Clinical Significance of the First Biopsy in Device-Assisted Enteroscopy in Patients with Small Bowel Diseases: A KASID Multicenter Studyopen access
- Authors
- Goong, HJ[Goong, Hyeon Jeong]; Kim, TJ[Kim, Tae Joon]; Nam, K[Nam, Kwangwoo]; Park, J[Park, Jihye]; Kim, JO[Kim, Jin-Oh]; Kim, HG[Kim, Hyun Gun]; Ko, BM[Ko, Bong Min]; Jeon, SR[Jeon, Seong Ran]
- Issue Date
- Apr-2022
- Publisher
- MDPI
- Keywords
- device assisted enteroscopy; small bowel; biopsy
- Citation
- DIAGNOSTICS, v.12, no.4
- Indexed
- SCIE
SCOPUS
- Journal Title
- DIAGNOSTICS
- Volume
- 12
- Number
- 4
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/96936
- DOI
- 10.3390/diagnostics12040964
- ISSN
- 2075-4418
- Abstract
- Device-assisted enteroscopy (DAE) enables the direct visualization of small bowel lesions with histological diagnosis; however, few studies have described the diagnostic performance of enteroscopic biopsy. We investigated the diagnostic performance of enteroscopic biopsy. We used a nationwide multicenter enteroscopy database to identify patients who underwent DAE with biopsy for small bowel diseases. The patients were classified into the tumor and non-tumor groups according to the final diagnosis. They were also divided into diagnostic and non-diagnostic groups based on the enteroscopic biopsy results. The clinical significance of the first biopsy and histological diagnostic yield of DAE were analyzed. Among the 112 procedures investigated, 32 (28.9%) were diagnosed with tumors, and 80 (71.7%) were diagnosed with non-tumor diseases. The overall histological diagnostic yield of DAE was 43.7%. The histological diagnostic yield was significantly higher in the tumor than in the non-tumor group (81.2% vs. 28.8%, p < 0.001). The mean number of biopsies was significantly higher in the diagnostic than in the non-diagnostic group (5.6 +/- 3.3 vs. 3.7 +/- 2.1, p = 0.001). In the diagnostic group, 87.7% of the cases were histologically confirmed at the first biopsy. Therefore, the first biopsy should be performed carefully.
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Collections - Medicine > Department of Medicine > 1. Journal Articles
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