The Relationship between Late-Life Depression and Cognitive Function in Older Korean Adults: A Moderation Analysis of Physical Activity Combined with Lower-Body Muscle Strengthopen access
- Authors
- Kong, J[Kong, Jiyoung]; Kang, M[Kang, Minjeong]; Kang, H[Kang, Hyunsik]
- Issue Date
- Jul-2022
- Publisher
- MDPI
- Keywords
- physical activity; physical fitness; mental health; older adults
- Citation
- INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, v.19, no.14
- Indexed
- SCIE
SSCI
SCOPUS
- Journal Title
- INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
- Volume
- 19
- Number
- 14
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/98613
- DOI
- 10.3390/ijerph19148769
- ISSN
- 1661-7827
- Abstract
- Background: This study examined the relationship of physical activity (PA) combined with lower-body muscle strength to late-life depression and cognitive impairment in 10,097 participants (6062 females) >= 65 years of age. Methods: Exposures were PA, sit-to-stand test (STST), and depressive symptoms. Outcome was cognitive performance. Results: Depressed individuals had an increased risk of mild cognitive impairment (MCI; odds ratio (OR), adjusted OR = 1.845 and 95% confidence interval (CI) = 1.580-2.154, p < 0.001) compared with non-depressed individuals. Individuals who had insufficient PA and a poor STST and either insufficient PA or a poor STST had an increased risk of MCI (adjusted OR = 1.329 and 95% CI = 1.209-1.46, p < 0.001 and adjusted OR = 2.822 and 95% CI = 2.488-3.200, p < 0001, respectively) compared with individuals who had sufficient PA and a good STST. A significant moderation effect of PA combined with lower-body muscle strength on the relationship between depression and cognitive function was observed (beta = -1.3923; 95% CI = -2.1505 to -0.6341, p < 0.003). Conclusions: The negative effect of late-life depression on cognitive function was incremental in the order of sufficient PA and a good STST, insufficient PA or a poor STST, and insufficient PA and a poor STST.
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Collections - Sport Science > Department of Sport Science > 1. Journal Articles
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