Detailed Information
Cited 0 time in 
Cited 3 time in 
Cited 3 time in
Metadata Downloads
Functional angiography-derived index of microcirculatory resistance validated with microvascular obstruction in cardiac magnetic resonance after STEMI [Índice de resistencia microcirculatoria y obstrucción microvascular en la resonancia magnética cardiaca tras un IAMCEST]
- Authors
- Shin, D.[Shin, D.]; Kim, J.[Kim, J.]; Choi, K.H.[Choi, K.H.]; Dai, N.[Dai, N.]; Li, Y.[Li, Y.]; Lee, S.H.[Lee, S.H.]; Joh, H.S.[Joh, H.S.]; Kim, H.K.[Kim, H.K.]; Kim, S.-M.[Kim, S.-M.]; Ha, S.J.[Ha, S.J.]; Jang, M.J.[Jang, M.J.]; Park, T.K.[Park, T.K.]; Yang, J.H.[Yang, J.H.]; Song, Y.B.[Song, Y.B.]; Hahn, J.-Y.[Hahn, J.-Y.]; Choi, S.-H.[Choi, S.-H.]; Choe, Y.H.[Choe, Y.H.]; Gwon, H.-C.[Gwon, H.-C.]; Lee, J.M.[Lee, J.M.]
- Issue Date
- Oct-2022
- Publisher
- Ediciones Doyma, S.L.
- Keywords
- Cardiac magnetic resonance imaging; Index of microcirculatory resistance; Microvascular obstruction; Myocardial infarction; ST-elevation myocardial infarction
- Citation
- Revista Espanola de Cardiologia, v.75, no.10, pp.787 - 797
- Indexed
- SCIE
SCOPUS
- Journal Title
- Revista Espanola de Cardiologia
- Volume
- 75
- Number
- 10
- Start Page
- 787
- End Page
- 797
- ISSN
- 0300-8932
- Abstract
- Introduction and objectives: The index of microcirculatory resistance (IMR) measured after primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) is associated with microvascular obstruction (MVO) and adverse clinical events. To evaluate MVO after successful primary PCI for STEMI without pressure wires or hyperemic agents, we investigated the feasibility and usefulness of functional angiography-derived IMR (angio-IMR). Methods: The current study included a total of 285 STEMI patients who underwent primary PCI and cardiac magnetic resonance (CMR). Angio-IMR of the culprit vessel after successful primary PCI was calculated using commercial software. MVO, infarct size, and myocardial salvage index were assessed using CMR, which was obtained a median of 3.0 days [interquartile range, 3.0-5.0] after primary PCI. Results: Among the total population, 154 patients (54.0%) showed elevated angio-IMR (> 40 U) in the culprit vessel. MVO was significantly more prevalent in patients with angio-IMR > 40 U than in those with angio-IMR ≤ 40 U (88.3% vs 32.1%, P < .001). Infarct size, extent of MVO, and area at risk were significantly larger in patients with angio-IMR > 40 U than in those with angio-IMR ≤ 40 U (P < .001 for all). Angio-IMR showed a significantly higher discriminatory ability for the presence of MVO than thrombolysis in myocardial infarction flow grade or myocardial blush grade (area under the curve: 0.821, 0.504, and 0.496, respectively, P < .001). Conclusions: Angio-IMR was significantly associated with CMR-derived infarct size, extent of MVO, and area at risk. An elevated angio-IMR (> 40 U) after primary PCI for STEMI was highly predictive of the presence of MVO in CMR. This trial was registered at ClnicalTrialsgov (Identifier: NCT04828681). © 2022 Sociedad Española de Cardiología
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - Medicine > Department of Medicine > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.