The impact of Hunner lesion-type interstitial cystitis/bladder pain syndrome on health-related quality of life and the effects of transurethral ablation
- Authors
- Ko, K.J.[Ko, K.J.]; Lim, J.[Lim, J.]; Yu, J.[Yu, J.]; Kang, D.[Kang, D.]; Cho, J.[Cho, J.]; Lee, K.-S.[Lee, K.-S.]
- Issue Date
- Nov-2022
- Publisher
- Springer Science and Business Media Deutschland GmbH
- Keywords
- Bladder pain syndrome; EQ-5D; Health-related quality of life. interstitial cystitis; Pain; Therapeutics
- Citation
- Quality of Life Research, v.31, no.11, pp.3221 - 3228
- Indexed
- SCIE
SSCI
SCOPUS
- Journal Title
- Quality of Life Research
- Volume
- 31
- Number
- 11
- Start Page
- 3221
- End Page
- 3228
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/99858
- DOI
- 10.1007/s11136-022-03183-2
- ISSN
- 0962-9343
- Abstract
- Purpose: Interstitial cystitis/bladder pain syndrome (IC/BPS) has a negative impact on quality of life. We compared health-related quality of life (HRQoL) of patients with IC/BPS with patients having other diseases using the EuroQol five-dimension (EQ-5D) and evaluated whether the HRQoL is improved after surgery. Methods: We compared EQ-5D of patients with Hunner lesion type IC/BPS with patients who had other diseases that cause chronic and severe pain including arthritis and cancer from a cross-sectional analysis of responses to the 2012–2016 Korea National Health and Nutrition Examination Survey. Changes in EQ-5D after transurethral coagulation (TUC) or resection (TUR) were measured in the IC/BPS participants. Results: Compared to the EQ-5D index of normal population, patients with arthritis, cancer and IC/BPS had − 0.07 (95% CI − 0.07, − 0.06), − 0.01 (95% CI − 0.02, − 0.01), and − 0.21 (95% CI − 0.23, − 0.20) lower scores, respectively. Patients with IC/BPS were 35.9, 9.24, and 9.05 times more likely to have “extreme problem” in pain/discomfort, anxiety/depression, and usual activities EQ-5D domains, respectively, than patients without arthritis/cancer. After TUC or TUR, EQ-5D index was 0.90 in the TUC group and 0.92 in the TUR group. Conclusion: IC/BPS patients have worse HRQoL than healthy individuals. However, after surgical treatment, HRQoL is restored to a level close to normal. © 2022, The Author(s), under exclusive licence to Springer Nature Switzerland AG.
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Collections - Samsung Advanced Institute for Health Sciences and Technology, SKKU > Samsung Advanced Institute for Health Sciences and Technology, SKKU > 1. Journal Articles
- Medicine > Department of Medicine > 1. Journal Articles
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