Haplotype Phylogeny of a 200kb Region in the Human Chromosome X Terminal Band (q28)
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김상수 | - |
dc.date.available | 2018-05-10T16:05:02Z | - |
dc.date.created | 2018-04-17 | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 1598-866X | - |
dc.identifier.uri | http://scholarworks.bwise.kr/ssu/handle/2018.sw.ssu/16974 | - |
dc.description.abstract | The haplotypes of a 200 kb region in the human chromosome X terminal band (q28) were analyzed using the International HapMap Project PhaseII data, which had been collected for three analysis panels (YRI, CEU, and CHB+JPT). When multiple linkage disequilibrium blocks were encountered for a panel, the neighboring haplotypes that had crossover rate of 5% or more in the panel were combined to generate 'haploid' configurations. This resulted in 8, 7, and 5 'haploid' configurations for the panels of YRI, CEU, and CHB+JPT, respectively. The multiple sequence alignment of these 'haploids' was used for the calculation of allele-sharing distances and the subsequent principal coordinate analysis. Two 'haploids' in CEU and CHB+JPT were hypothesized as 'parental' in light of the observations that the successive recombinants of these haploids can model two other haploids in CEU and CHB+JPT, and that their configurations were consistent with those in YRI. This study demonstrates the utility of haplotype phylogeny in understanding population evolution. | - |
dc.publisher | 한국유전체학회 | - |
dc.relation.isPartOf | Genomics & Informatics | - |
dc.subject | haplotype | - |
dc.subject | SNP | - |
dc.subject | phylogeny | - |
dc.subject | haploview | - |
dc.subject | HapMap | - |
dc.title | Haplotype Phylogeny of a 200kb Region in the Human Chromosome X Terminal Band (q28) | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | Genomics & Informatics, v.6, no.3, pp.130 - 135 | - |
dc.identifier.kciid | ART001279535 | - |
dc.description.journalClass | 2 | - |
dc.citation.endPage | 135 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 130 | - |
dc.citation.title | Genomics & Informatics | - |
dc.citation.volume | 6 | - |
dc.contributor.affiliatedAuthor | 김상수 | - |
dc.subject.keywordAuthor | haplotype | - |
dc.subject.keywordAuthor | SNP | - |
dc.subject.keywordAuthor | phylogeny | - |
dc.subject.keywordAuthor | haploview | - |
dc.subject.keywordAuthor | HapMap | - |
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