Antiobesity effect of trans-10,cis-12-conjugated linoleic acid-producing Lactobacillus plantarum PL62 on diet-induced obese mice
DC Field | Value | Language |
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dc.contributor.author | Lee, K. | - |
dc.contributor.author | Paek, K. | - |
dc.contributor.author | Lee, H. Y. | - |
dc.contributor.author | Park, J. H. | - |
dc.contributor.author | Lee, Y. | - |
dc.date.available | 2018-05-10T16:34:41Z | - |
dc.date.created | 2018-04-17 | - |
dc.date.issued | 2007-10 | - |
dc.identifier.issn | 1364-5072 | - |
dc.identifier.uri | http://scholarworks.bwise.kr/ssu/handle/2018.sw.ssu/17750 | - |
dc.description.abstract | Aims: To observe the antiobesity activity of trans-10,cis-12-conjugated linoleic acid (CLA)-producing lactobacillus in mice. Methods and Results: Lactobacillus plantarum PL62, which can grow in the presence of linoleic acid, was selected and studied. The culture supernatant of Lact. plantarum PL62 contained trans-10,cis-12-conjugated linoleic acid (6.4 mu g ml(-1)), and the crude enzyme prepared from washed cells produced trans-10,cis-12 CLA (1395 mu g mg(-1) protein). Lact. plantarum PL62 reduced the weights of epididymal, inguinal, mesenteric, and perirenal white adipose tissues and significantly reduced the blood levels of total glucose and body weights of mice (P < 0.01). Conclusions: trans-10,cis-12-CLA-producing Lact. plantarum PL62 can exert the same antiobesity activity as trans-10,cis-12-CLA in mice. Significance and impact of the study: trans-10,cis-12-CLA-producing Lactobacillus can be a replacement for CLA for obesity treatment via the continuous production of trans-10,cis-12-CLA. The results provide a novel opportunity to develop foods with antiobesity activity. | - |
dc.publisher | BLACKWELL PUBLISHING | - |
dc.relation.isPartOf | JOURNAL OF APPLIED MICROBIOLOGY | - |
dc.subject | BODY-COMPOSITION | - |
dc.subject | RIBOSOMAL-RNA | - |
dc.subject | WASHED CELLS | - |
dc.subject | ACIDOPHILUS | - |
dc.subject | FAT | - |
dc.subject | METABOLISM | - |
dc.subject | ADIPOSE | - |
dc.subject | HUMANS | - |
dc.subject | ISOMER | - |
dc.subject | TISSUE | - |
dc.title | Antiobesity effect of trans-10,cis-12-conjugated linoleic acid-producing Lactobacillus plantarum PL62 on diet-induced obese mice | - |
dc.type | Article | - |
dc.identifier.doi | 10.1111/j.1365-2672.2007.03336.x | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | JOURNAL OF APPLIED MICROBIOLOGY, v.103, no.4, pp.1140 - 1146 | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000249825300044 | - |
dc.identifier.scopusid | 2-s2.0-34848873080 | - |
dc.citation.endPage | 1146 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 1140 | - |
dc.citation.title | JOURNAL OF APPLIED MICROBIOLOGY | - |
dc.citation.volume | 103 | - |
dc.contributor.affiliatedAuthor | Paek, K. | - |
dc.type.docType | Article | - |
dc.description.oadoiVersion | published | - |
dc.subject.keywordAuthor | antiobesity | - |
dc.subject.keywordAuthor | conjugated linoleic acid | - |
dc.subject.keywordAuthor | Lactobacillus plantarum | - |
dc.subject.keywordAuthor | probiotic | - |
dc.subject.keywordAuthor | trans-10 | - |
dc.subject.keywordAuthor | cis-12-CLA | - |
dc.subject.keywordPlus | BODY-COMPOSITION | - |
dc.subject.keywordPlus | RIBOSOMAL-RNA | - |
dc.subject.keywordPlus | WASHED CELLS | - |
dc.subject.keywordPlus | ACIDOPHILUS | - |
dc.subject.keywordPlus | FAT | - |
dc.subject.keywordPlus | METABOLISM | - |
dc.subject.keywordPlus | ADIPOSE | - |
dc.subject.keywordPlus | HUMANS | - |
dc.subject.keywordPlus | ISOMER | - |
dc.subject.keywordPlus | TISSUE | - |
dc.description.journalRegisteredClass | scopus | - |
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