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AIDS환자 치료를 위한 점진적 약물감소기법에 감염속도상수가 미치는 영향The influence of infection ratio on Gradual Reduction of Drug Dose for the treatment of AIDS patients
- Other Titles
- The influence of infection ratio on Gradual Reduction of Drug Dose for the treatment of AIDS patients
- Issue Date
- Jan-2007
- Publisher
- 대한전기학회
- Keywords
- AIDS; HIV; Non-progressor; Infection ratio; Bifurcation Diagram; Lyapunov stability1. 서 론 † 교신저자; 正會員 : 崇實大 工大 電氣工學部 助敎授工博 E-mail : nhjo@ssu.ac.kr*學生會員 : 崇實大 工大 電氣工學部 제어정보처리연구실 석사과정接受日字 : 2006年 8月 20日最終完了 : 2006年 11月 5日
- Citation
- 전기학회논문지ABCD, v.56, no.1, pp.174 - 182
- Journal Title
- 전기학회논문지ABCD
- Volume
- 56
- Number
- 1
- Start Page
- 174
- End Page
- 182
- ISSN
- 1229-2443
- Abstract
- - In this paper, we study the influence of infection ratio on gradual reduction of drug dose for the five state HIV infection model that explicitly includes the population of the virus. We first compute all equilibrium points of the model and investigate the stabilities of them. As a result, a bifurcation diagram is obtained which shows a change in the equilibrium points, or in their stability properties, as the drug effect is varied from 0 to 1(alternatively, drug dose is changed from 1 to 0). Based on the bifurcation diagram, we show that the gradual reduction of drug dose can be applied for the treatment of AIDS patients. Moreover, we analyze the influence of the variation of infection ratio on the gradual reduction treatment. Computer simulation results are also presented to validate the proposed results.
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Related Researcher
- Jo, Nam Hoon
- College of Engineering (School of Electrical Engineering)