The incidence rates and risk factors of Parkinson disease in patients with psoriasis: A nationwide population-based cohort study
DC Field | Value | Language |
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dc.contributor.author | Lee, Jihyun | - |
dc.contributor.author | Han, Kyoungdo | - |
dc.contributor.author | Gee, Heonyung | - |
dc.date.available | 2020-09-14T08:05:23Z | - |
dc.date.created | 2020-06-18 | - |
dc.date.issued | 2020-12 | - |
dc.identifier.issn | 0190-9622 | - |
dc.identifier.uri | http://scholarworks.bwise.kr/ssu/handle/2018.sw.ssu/38634 | - |
dc.description.abstract | Background: The association between psoriasis and Parkinson disease has not been established. Objective: To determine the incidence rates and risk factors of Parkinson disease in patients with psoriasis. Methods: We conducted a nationwide population-based cohort study. The data from patients with psoriasis (N = 548,327, ≥20 years of age, 53.32% men and 46.68% women) and age- and sex-matched control patients (N = 2,741,635) without psoriasis were analyzed in this study. Results: The incidence rates of Parkinson disease per 1000 person-years were 0.673 and 0.768 in the control and psoriasis groups, respectively. The psoriasis group showed a significantly increased risk of developing Parkinson disease (hazard ratio [HR] 1.091, 95% confidence interval [CI] 1.029-1.115). The risk of Parkinson disease was significantly higher among the psoriasis patients who were not receiving systemic therapy (HR 1.093, 95% CI 1.031-1.159) and lower among the psoriasis patients on systemic therapy (HR 1.04, 95% CI 0.806-1.316). Limitations: The limitations of this study included the retrospective design, patient inclusion solely on the basis of diagnostic codes, and unavailability of data on confounding factors. Conclusion: Systemic anti-inflammatory agents might mitigate the risk of Parkinson disease in psoriasis patients. © 2019 American Academy of Dermatology, Inc. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Mosby Inc. | - |
dc.relation.isPartOf | Journal of the American Academy of Dermatology | - |
dc.title | The incidence rates and risk factors of Parkinson disease in patients with psoriasis: A nationwide population-based cohort study | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.jaad.2019.07.012 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | Journal of the American Academy of Dermatology, v.83, no.6, pp.1688 - 1695 | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000616663500062 | - |
dc.identifier.scopusid | 2-s2.0-85075144106 | - |
dc.citation.endPage | 1695 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1688 | - |
dc.citation.title | Journal of the American Academy of Dermatology | - |
dc.citation.volume | 83 | - |
dc.contributor.affiliatedAuthor | Han, Kyoungdo | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.subject.keywordAuthor | cohort study | - |
dc.subject.keywordAuthor | incidence | - |
dc.subject.keywordAuthor | Parkinson disease | - |
dc.subject.keywordAuthor | population-based | - |
dc.subject.keywordAuthor | psoriasis | - |
dc.subject.keywordAuthor | risk factor | - |
dc.relation.journalResearchArea | Dermatology | - |
dc.relation.journalWebOfScienceCategory | Dermatology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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