Long-term risk of congestive heart failure in younger breast cancer survivors: A nationwide study by the SMARTSHIP group
DC Field | Value | Language |
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dc.contributor.author | Lee, Jihyoun | - |
dc.contributor.author | Hur, Ho | - |
dc.contributor.author | Lee, Jong Won | - |
dc.contributor.author | Youn, Hyun Jo | - |
dc.contributor.author | Han, Kyungdo | - |
dc.contributor.author | Kim, Nam Won | - |
dc.contributor.author | Jung, So-Youn | - |
dc.contributor.author | Kim, Zisun | - |
dc.contributor.author | Kim, Ku Sang | - |
dc.contributor.author | Lee, Min Hyuk | - |
dc.contributor.author | Han, Se-Hwan | - |
dc.contributor.author | Jung, Sung Hoo | - |
dc.contributor.author | Chung, Il Yong | - |
dc.date.available | 2020-09-14T08:06:40Z | - |
dc.date.created | 2020-06-18 | - |
dc.date.issued | 2020-01 | - |
dc.identifier.issn | 0008-543X | - |
dc.identifier.uri | http://scholarworks.bwise.kr/ssu/handle/2018.sw.ssu/38797 | - |
dc.description.abstract | Background There is a controversy about late-onset congestive heart failure (CHF) among breast cancer survivors. This study investigated the incidence rate and risk factors of late-onset CHF more than 2 years after the breast cancer diagnosis. Methods A nationwide, retrospective study was conducted with the National Health Information Database. With 1:3 age- and sex-matched noncancer controls, Cox proportional hazard regression models were used to analyze the incidence and risk factors of late CHF. The cumulative incidence rate of late CHF was evaluated with a Kaplan-Meier analysis and a log-rank test. Results A total of 91,227 cases (286,480 person-years) and 273,681 controls (884,349 person-years) were evaluated between January 2007 and December 2013. The risks of late CHF were higher in cases than controls (hazard ratio [HR], 1.396; 95% confidence interval [CI], 1.268-1.538). Younger survivors (age <= 50 years) showed a higher risk of late CHF than their younger counterparts (HR, 2.903; 95% CI, 2.425-3.474). Although older age was a risk factor for late CHF, older survivors (age >= 66 years) showed no difference in the risk of late CHF in comparison with their counterparts (HR, 0.906; 95% CI, 0.757-1.084). Anthracyclines and taxanes were risk factors for late CHF, although trastuzumab, radiation, and endocrine therapy were not. Conclusions Young breast cancer survivors have a greater risk of late CHF than the young population without cancer. More attention should be paid to young breast cancer survivors who receive taxane- or anthracycline-based regimens over the long term. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.relation.isPartOf | CANCER | - |
dc.title | Long-term risk of congestive heart failure in younger breast cancer survivors: A nationwide study by the SMARTSHIP group | - |
dc.type | Article | - |
dc.identifier.doi | 10.1002/cncr.32485 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | CANCER, v.126, no.1, pp.181 - 188 | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000483905200001 | - |
dc.citation.endPage | 188 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 181 | - |
dc.citation.title | CANCER | - |
dc.citation.volume | 126 | - |
dc.contributor.affiliatedAuthor | Han, Kyungdo | - |
dc.type.docType | Article; Early Access | - |
dc.description.isOpenAccess | N | - |
dc.subject.keywordAuthor | adjuvant | - |
dc.subject.keywordAuthor | adverse effects | - |
dc.subject.keywordAuthor | breast neoplasms | - |
dc.subject.keywordAuthor | chemotherapy | - |
dc.subject.keywordAuthor | heart diseases | - |
dc.subject.keywordAuthor | survivorship | - |
dc.subject.keywordPlus | CARDIOTOXICITY | - |
dc.subject.keywordPlus | ANTHRACYCLINE | - |
dc.subject.keywordPlus | CHEMOTHERAPY | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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