Association Between the Persistence of Obesity and the Risk of Gastric Cancer: A Nationwide Population-Based Study
DC Field | Value | Language |
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dc.contributor.author | 임주현 | - |
dc.contributor.author | 신철민 | - |
dc.contributor.author | 한경도 | - |
dc.contributor.author | 이승우 | - |
dc.contributor.author | 진은효 | - |
dc.contributor.author | 최윤진 | - |
dc.contributor.author | 윤혁 | - |
dc.contributor.author | 박영수 | - |
dc.contributor.author | 김나영 | - |
dc.contributor.author | 이동호 | - |
dc.date.accessioned | 2022-01-25T03:40:07Z | - |
dc.date.available | 2022-01-25T03:40:07Z | - |
dc.date.created | 2022-01-25 | - |
dc.date.issued | 2022-01 | - |
dc.identifier.issn | 1598-2998 | - |
dc.identifier.uri | http://scholarworks.bwise.kr/ssu/handle/2018.sw.ssu/41683 | - |
dc.description.abstract | Purpose There remains controversy about relationship between obesity and gastric cancer. We aimed to examine the association using obesity-persistence. Materials and Methods We analyzed a nationwide population-based cohort which underwent health check-up between 2009 and 2012. Among them, those who had annual examinations during the last 5 years were selected. Gastric cancer risk was compared between those without obesity during the 5 years (never-obesity group) and those with obesity diagnosis during the 5 years (non-persistent obesity group; persistent obesity group). Results Among 2,757,017 individuals, 13,441 developed gastric cancer after median 6.78 years of follow-up. Gastric cancer risk was the highest in persistent obesity group (incidence rate [IR], 0.89/1,000 person-years; hazard ratio [HR], 1.197; 95% confidence interval [CI], 1.117 to 1.284), followed by non-persistent obesity group (IR, 0.83/1,000 person-years; HR, 1.113; 95% CI, 1.056 to 1.172) compared with never-obesity group. In subgroup analysis, this positive relationship was true among those < 65 years old and male. Among heavy-drinkers, the impact of obesity-persistence on the gastric cancer risk far increased (non-persistent obesity: HR, 1.297; 95% CI, 1.094 to 1.538; persistent obesity: HR, 1.351; 95% CI, 1.076 to 1.698). Conclusion Obesity-persistence is associated with increased risk of gastric cancer in a dose-response manner, especially among male < 65 years old. The risk raising effect was much stronger among heavy-drinkers. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | 대한암학회 | - |
dc.relation.isPartOf | Cancer Research and Treatment | - |
dc.title | Association Between the Persistence of Obesity and the Risk of Gastric Cancer: A Nationwide Population-Based Study | - |
dc.title.alternative | Association Between the Persistence of Obesity and the Risk of Gastric Cancer: A Nationwide Population-Based Study | - |
dc.type | Article | - |
dc.identifier.doi | 10.4143/crt.2021.130 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | Cancer Research and Treatment, v.54, no.1, pp.199 - 207 | - |
dc.identifier.kciid | ART002802693 | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000788852400019 | - |
dc.identifier.scopusid | 2-s2.0-85111525139 | - |
dc.citation.endPage | 207 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 199 | - |
dc.citation.title | Cancer Research and Treatment | - |
dc.citation.volume | 54 | - |
dc.contributor.affiliatedAuthor | 한경도 | - |
dc.identifier.url | https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002802693 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.subject.keywordAuthor | Obesity | - |
dc.subject.keywordAuthor | Stomach neoplasms | - |
dc.subject.keywordAuthor | Dose-response relationship | - |
dc.subject.keywordPlus | BODY-MASS INDEX | - |
dc.subject.keywordPlus | STOMACH-CANCER | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | EPIDEMIOLOGY | - |
dc.subject.keywordPlus | SMOKING | - |
dc.subject.keywordPlus | MEN | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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