Color-Tunable Indolizine-Based Fluorophores and Fluorescent pH Sensor
- Authors
- Kim, Taegwan; Kim, Jonghoon
- Issue Date
- Jan-2022
- Publisher
- MDPI
- Keywords
- indolizine; fluorescence; fluorophore design; pH sensor; intramolecular charge transfer (ICT)
- Citation
- MOLECULES, v.27, no.1
- Journal Title
- MOLECULES
- Volume
- 27
- Number
- 1
- URI
- http://scholarworks.bwise.kr/ssu/handle/2018.sw.ssu/41689
- DOI
- 10.3390/molecules27010012
- ISSN
- 1420-3049
- Abstract
- A new fluorescent indolizine-based scaffold was developed using a straightforward synthetic scheme starting from a pyrrole ring. In this fluorescent system, an N,N-dimethylamino group in the aryl ring at the C-3 position of indolizine acted as an electron donor and played a crucial role in inducing a red shift in the emission wavelength based on the ICT process. Moreover, various electron-withdrawing groups, such as acetyl and aldehyde, were introduced at the C-7 position of indolizine, to tune and promote the red shift of the emission wavelength, resulting in a color range from blue to orange (462-580 nm). Furthermore, the ICT effect in indolizine fluorophores allowed the design and development of new fluorescent pH sensors of great potential in the field of fluorescence bioimaging and sensors.
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Collections - College of Natural Sciences > Department of Chemistry > 1. Journal Articles
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