A transdisciplinary approach to understand the epigenetic basis of race/ethnicity health disparities
- Authors
- Salas, Lucas A.; Peres, Lauren C.; Thayer, Zaneta M.; Smith, Rick W. A.; Guo, Yichen; Chung, Wonil; Si, Jiahui; Liang, Liming
- Issue Date
- Nov-2021
- Publisher
- FUTURE MEDICINE LTD
- Keywords
- anthropology; cancer health disparities; computational biology; DNA methylation; epigenomics; ethnic groups; health status disparities; molecular epidemiology
- Citation
- EPIGENOMICS, v.13, no.21, pp.1761 - 1770
- Journal Title
- EPIGENOMICS
- Volume
- 13
- Number
- 21
- Start Page
- 1761
- End Page
- 1770
- URI
- http://scholarworks.bwise.kr/ssu/handle/2018.sw.ssu/41875
- DOI
- 10.2217/epi-2020-0080
- ISSN
- 1750-1911
- Abstract
- Health disparities correspond to differences in disease burden and mortality among socially defined population groups. Such disparities may emerge according to race/ethnicity, socioeconomic status and a variety of other social contexts, and are documented for a wide range of diseases. Here, we provide a transdisciplinary perspective on the contribution of epigenetics to the understanding of health disparities, with a special emphasis on disparities across socially defined racial/ethnic groups. Scientists in the fields of biological anthropology, bioinformatics and molecular epidemiology provide a summary of theoretical, statistical and practical considerations for conducting epigenetic health disparities research, and provide examples of successful applications from cancer research using this approach.
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Collections - College of Natural Sciences > ETC > 1. Journal Articles
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