Longitudinal Patterns in Antithrombotic Therapy in Patients with Atrial Fibrillation after Percutaneous Coronary Intervention in the Non-Vitamin K Oral Anticoagulant Era: A Nationwide Population-Based Study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Jiesuck | - |
dc.contributor.author | Jung, Jin-Hyung | - |
dc.contributor.author | Choi, Eue-Keun | - |
dc.contributor.author | Lee, Seung-Woo | - |
dc.contributor.author | Kwon, Soonil | - |
dc.contributor.author | Lee, So-Ryoung | - |
dc.contributor.author | Kang, Jeehoon | - |
dc.contributor.author | Han, Kyung-Do | - |
dc.contributor.author | Park, Kyung-Woo | - |
dc.contributor.author | Oh, Seil | - |
dc.contributor.author | Lip, Gregory Y. H. | - |
dc.date.accessioned | 2022-03-11T03:40:38Z | - |
dc.date.available | 2022-03-11T03:40:38Z | - |
dc.date.created | 2022-03-11 | - |
dc.date.issued | 2021-04 | - |
dc.identifier.issn | 2077-0383 | - |
dc.identifier.uri | http://scholarworks.bwise.kr/ssu/handle/2018.sw.ssu/41996 | - |
dc.description.abstract | We investigated whether longitudinal patterns in antithrombotic therapy have changed after the introduction of non-vitamin K oral anticoagulants (NOACs) in patients with atrial fibrillation (AF) who underwent percutaneous coronary intervention (PCI). Using a claims database of the Korean AF population who underwent PCI between 2012 and 2016 (n = 18,691), we analyzed prescription records of oral anticoagulants (OACs) and antiplatelets at 3-month intervals over 2 years after PCI. The study population was stratified (pre-NOAC, transition, and NOAC era) using time-periods of NOAC introduction in Korea and an expansion of reimbursement for NOAC in AF as indicators. The overall rates of OAC were low at baseline (24.9%, 26.9%, and 35.2% in pre-NOAC, transition, and NOAC era, respectively), contrary to high rates of dual antiplatelet therapy (DAPT) (73.3%, 71.4%, and 63.6%). However, OAC prescription rates were increased at 1-year (18.5%, 22.5%, and 31.6%), and 2-year follow-up (17.8%, 24.2%, and 31.8%) from pre-NOAC to NOAC era. In NOAC era, 63.5% of baseline OAC prescriptions comprised NOAC, of which 96.4% included triple therapy with DAPT. Over 2 years, we observed increasing rates of double therapy with a single antiplatelet (18.3% and 20.0% at 1- and 2-year follow-up) and OAC monotherapy (2.7% and 8.9% at 1- and 2-year follow-up). | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL MEDICINE | - |
dc.title | Longitudinal Patterns in Antithrombotic Therapy in Patients with Atrial Fibrillation after Percutaneous Coronary Intervention in the Non-Vitamin K Oral Anticoagulant Era: A Nationwide Population-Based Study | - |
dc.type | Article | - |
dc.identifier.doi | 10.3390/jcm10071505 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL MEDICINE, v.10, no.7 | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000638620700001 | - |
dc.identifier.scopusid | 2-s2.0-85114082508 | - |
dc.citation.number | 7 | - |
dc.citation.title | JOURNAL OF CLINICAL MEDICINE | - |
dc.citation.volume | 10 | - |
dc.contributor.affiliatedAuthor | Han, Kyung-Do | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.subject.keywordAuthor | atrial fibrillation | - |
dc.subject.keywordAuthor | percutaneous coronary intervention | - |
dc.subject.keywordAuthor | anticoagulation | - |
dc.subject.keywordAuthor | antiplatelets | - |
dc.subject.keywordAuthor | non-vitamin K oral anticoagulant | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
Soongsil University Library 369 Sangdo-Ro, Dongjak-Gu, Seoul, Korea (06978)02-820-0733
COPYRIGHT ⓒ SOONGSIL UNIVERSITY, ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.