Metal-Enhanced Fluorescence for Alpha-Fetoprotein Detection and for SERS Using Hybrid Nanoparticles of Magnetic Cluster Core-Plasmonic Shell Composite
DC Field | Value | Language |
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dc.contributor.author | Phuc, Lam Gia | - |
dc.contributor.author | Do, Phuong Que Tran | - |
dc.contributor.author | Ta, Hanh Kieu Thi | - |
dc.contributor.author | Dang, Vinh Quang | - |
dc.contributor.author | Joo, Sang-Woo | - |
dc.contributor.author | Manh, Do Hung | - |
dc.contributor.author | Bach, Ta Ngoc | - |
dc.contributor.author | Van, Tran T. T. | - |
dc.contributor.author | Tran, Nhu Hoa Thi | - |
dc.date.accessioned | 2023-03-23T07:40:05Z | - |
dc.date.available | 2023-03-23T07:40:05Z | - |
dc.date.created | 2023-02-27 | - |
dc.date.issued | 2023-01 | - |
dc.identifier.issn | 2227-9040 | - |
dc.identifier.uri | http://scholarworks.bwise.kr/ssu/handle/2018.sw.ssu/43494 | - |
dc.description.abstract | We demonstrated that the hybrid core-shell nanostructure of Fe3O4 (core) and gold (shell) could be a good substrate candidate both for metal-enhanced fluorescence (MEF) and surface-enhanced Raman spectroscopy (SERS). The magnetic properties of the core material could provide functionalities such as the magnetically induced aggregation/distribution of nanostructures to increase the hot-spot density, while the nano-thickness gold shell allows for the plasmonic enhancement of both fluorescence and SERS. The gold-capped magnetic (Fe3O4) nanoparticles (GMPs) were facilely synthesized using a newly developed chemical method. The relative molar ratio of the constituent materials of the core-shell composite was optimized for tuning the plasmonic resonance wavelengths for MEF and SERS. We employed GMP-based MEF to detect alpha-fetoprotein (AFP), with concentrations ranging from 0.05 to 1000 ng/mL, and obtained a limit of detection (LOD) as low as 3.8 x 10(-4) ng/mL. The signal enhancement factor (EF) in the GMP-based MEF was 1.5 at maximum. In addition, the GMPs were used in SERS to detect rhodamine B (RhB). Its LOD was 3.5 x 10(-12) M, and the EF was estimated to be about 2 x 10(8). The hybrid core-shell nanoparticles could find potential applications in diagnostic assays based on MEF and SERS in various fields such as food verification, environmental testing/monitoring, and disease diagnosis. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.relation.isPartOf | CHEMOSENSORS | - |
dc.title | Metal-Enhanced Fluorescence for Alpha-Fetoprotein Detection and for SERS Using Hybrid Nanoparticles of Magnetic Cluster Core-Plasmonic Shell Composite | - |
dc.type | Article | - |
dc.identifier.doi | 10.3390/chemosensors11010056 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | CHEMOSENSORS, v.11, no.1 | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000917027600001 | - |
dc.identifier.scopusid | 2-s2.0-85146804866 | - |
dc.citation.number | 1 | - |
dc.citation.title | CHEMOSENSORS | - |
dc.citation.volume | 11 | - |
dc.contributor.affiliatedAuthor | Joo, Sang-Woo | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.subject.keywordAuthor | cluster-core shell | - |
dc.subject.keywordAuthor | gold magnetic nanoparticles | - |
dc.subject.keywordAuthor | metal-enhanced fluorescence | - |
dc.subject.keywordAuthor | alpha-fetoprotein | - |
dc.subject.keywordAuthor | surface-enhanced Raman spectroscopy | - |
dc.subject.keywordPlus | GOLD NANOPARTICLES | - |
dc.subject.keywordPlus | TUMOR-MARKERS | - |
dc.subject.keywordPlus | RHODAMINE-B | - |
dc.subject.keywordPlus | RESONANCE | - |
dc.subject.keywordPlus | IMMUNOASSAY | - |
dc.subject.keywordPlus | BIOSENSOR | - |
dc.subject.keywordPlus | NANOSTRUCTURES | - |
dc.subject.keywordPlus | IMMUNOSENSOR | - |
dc.subject.keywordPlus | ABSORPTION | - |
dc.subject.keywordPlus | WAVELENGTH | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Electrochemistry | - |
dc.relation.journalResearchArea | Instruments & Instrumentation | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Electrochemistry | - |
dc.relation.journalWebOfScienceCategory | Instruments & Instrumentation | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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