Cardiovascular Outcomes according to Comorbidities and Low-Density Lipoprotein Cholesterol in Korean People with Type 2 Diabetes Mellitus
DC Field | Value | Language |
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dc.contributor.author | Moon, M.K. | - |
dc.contributor.author | Noh, J. | - |
dc.contributor.author | Rhee, E.-J. | - |
dc.contributor.author | Park, S.H. | - |
dc.contributor.author | Kim, H.C. | - |
dc.contributor.author | Kim, B.J. | - |
dc.contributor.author | Kim, H.J. | - |
dc.contributor.author | Choi, S. | - |
dc.contributor.author | Na, J.O. | - |
dc.contributor.author | Hyun, Y.Y. | - |
dc.contributor.author | Kim, B.J. | - |
dc.contributor.author | Han, K.-D. | - |
dc.contributor.author | Jeong, I.-K. | - |
dc.contributor.author | the Committee of Practice Guideline of Korean Lipid and Atheroscelerosis | - |
dc.date.accessioned | 2023-04-27T01:40:07Z | - |
dc.date.available | 2023-04-27T01:40:07Z | - |
dc.date.created | 2023-04-13 | - |
dc.date.issued | 2023-01 | - |
dc.identifier.issn | 2233-6079 | - |
dc.identifier.uri | http://scholarworks.bwise.kr/ssu/handle/2018.sw.ssu/43792 | - |
dc.description.abstract | Background: There are no clear data to support the cardiovascular (CV) risk categories and low-density lipoprotein cholesterol (LDL-C) treatment goals in Korean people with type 2 diabetes mellitus (T2DM). We evaluated the incidence of cardiovascular disease (CVD) according to comorbidities and suggested LDL-C treatment goals in Korean people with T2DM in nationwide cohort data. Methods: Using the Korean National Health Insurance Service database, 248,002 people aged 30 to 90 years with T2DM who underwent routine health check-ups during 2009 were included. Subjects with previous CVD were excluded from the study. The primary outcome was incident CVD, defined as a composite of myocardial infarction and ischemic stroke during the follow-up period from 2009 to 2018. Results: The mean age of the study participants was 59.6±10.9 years, and median follow-up period was 9.3 years. CVD incidence increased in the order of DM duration of 5 years or more (12.04/1,000 person-years), hypertension (HT) (12.27/1,000 person-years), three or more CV risk factors (14.10/1,000 person-years), and chronic kidney disease (18.28/1,000 person-years). The risk of incident CVD increased linearly from an LDL-C level of ≥70 mg/dL in most patients with T2DM. In T2DM patients without HT or with a DM duration of less than 5 years, the CVD incidence increased from LDL-C level of ≥100 mg/dL. Conclusion: For primary prevention of CVD in Korean adults with T2DM, it can be helpful to lower LDL-C targets when there are chronic kidney disease, HT, a long duration of diabetes mellitus, or three or more CV risk factors. Copyright © 2023 Korean Diabetes Association. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Korean Diabetes Association | - |
dc.relation.isPartOf | Diabetes and Metabolism Journal | - |
dc.title | Cardiovascular Outcomes according to Comorbidities and Low-Density Lipoprotein Cholesterol in Korean People with Type 2 Diabetes Mellitus | - |
dc.type | Article | - |
dc.identifier.doi | 10.4093/dmj.2021.0344 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | Diabetes and Metabolism Journal, v.47, no.1, pp.45 - 58 | - |
dc.identifier.kciid | ART002926884 | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000931560600004 | - |
dc.identifier.scopusid | 2-s2.0-85147146722 | - |
dc.citation.endPage | 58 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 45 | - |
dc.citation.title | Diabetes and Metabolism Journal | - |
dc.citation.volume | 47 | - |
dc.contributor.affiliatedAuthor | Han, K.-D. | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.subject.keywordAuthor | Cardiovascular diseases | - |
dc.subject.keywordAuthor | Cholesterol | - |
dc.subject.keywordAuthor | Diabetes mellitus | - |
dc.subject.keywordAuthor | Dyslipidemias | - |
dc.subject.keywordAuthor | Korea | - |
dc.subject.keywordPlus | CORONARY-HEART-DISEASE | - |
dc.subject.keywordPlus | BODY-MASS INDEX | - |
dc.subject.keywordPlus | NONDIABETIC SUBJECTS | - |
dc.subject.keywordPlus | AMERICAN-COLLEGE | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | GUIDELINES | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalWebOfScienceCategory | Endocrinology & Metabolism | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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