Metabolic syndrome and the risk of abdominal aortic aneurysm: A nationwide cohort study
DC Field | Value | Language |
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dc.contributor.author | Cho, In Young | - |
dc.contributor.author | Koo, Hye Yeon | - |
dc.contributor.author | Han, Kyungdo | - |
dc.contributor.author | Lee, Kyu Na | - |
dc.contributor.author | Cho, Mihee | - |
dc.contributor.author | Jin, Sang-Man | - |
dc.contributor.author | Cho, Yang Hyun | - |
dc.contributor.author | Lee, Jun Ho | - |
dc.contributor.author | Park, Yang-Jin | - |
dc.contributor.author | Shin, Dong Wook | - |
dc.date.accessioned | 2024-02-02T08:01:05Z | - |
dc.date.available | 2024-02-02T08:01:05Z | - |
dc.date.issued | 2023-12 | - |
dc.identifier.issn | 0021-9150 | - |
dc.identifier.issn | 1879-1484 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/ssu/handle/2018.sw.ssu/49128 | - |
dc.description.abstract | Background and aims: The association between metabolic syndrome (MetS) and abdominal aortic aneurysm (AAA) remains unclear. We investigated the potential association between AAA and MetS and its components in a large population-based cohort. Methods: We used the Korean National Health Insurance Service database including 4,162,640 participants aged >= 50 years who received a routine health examination in 2009. Cox proportional hazards models were used to analyze the association between MetS and its components (elevated waist circumference, blood pressure, glucose, triglycerides, and reduced high-density lipoprotein cholesterol [HDL-C]) with AAA incidence, with adjustment for confounders. Results: During a median 9.4 years of follow-up, 18,160 participants developed incident AAA. MetS was associated with an increased risk of AAA compared to the non-MetS group (adjusted hazard ratio [aHR], 1.38; 95% confidence interval [CI], 1.34-1.43). Among the individual components, elevated waist circumference, blood pressure, triglycerides, and reduced HDL-C were associated with increased AAA risk, while elevated glucose alone was associated with reduced AAA risk (aHR, 0.85; 95% CI, 0.82-0.87). AAA risk also increased linearly with the increasing number of MetS components, with the highest risk found in the presence of all 5 components (aHR, 1.98, 95% CI, 1.83-2.15). Conclusions: MetS and its individual components, with the exclusion of elevated glucose, were associated with higher risk of AAA. Further studies are warranted to elucidate the association between MetS and AAA. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ELSEVIER IRELAND LTD | - |
dc.title | Metabolic syndrome and the risk of abdominal aortic aneurysm: A nationwide cohort study | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.atherosclerosis.2023.117329 | - |
dc.identifier.bibliographicCitation | ATHEROSCLEROSIS, v.386 | - |
dc.identifier.wosid | 001135484900001 | - |
dc.identifier.scopusid | 2-s2.0-85173994923 | - |
dc.citation.title | ATHEROSCLEROSIS | - |
dc.citation.volume | 386 | - |
dc.identifier.url | https://linkinghub.elsevier.com/retrieve/pii/S0021915023052504 | - |
dc.publisher.location | 아일랜드 | - |
dc.type.docType | Article; Early Access | - |
dc.description.isOpenAccess | N | - |
dc.subject.keywordAuthor | Metabolic syndrome | - |
dc.subject.keywordAuthor | Aneurysm | - |
dc.subject.keywordAuthor | Abdominal aortic aneurysm | - |
dc.subject.keywordAuthor | Cohort study | - |
dc.subject.keywordPlus | OBESITY | - |
dc.subject.keywordPlus | EVENTS | - |
dc.subject.keywordPlus | HEALTH | - |
dc.subject.keywordPlus | EPIDEMIOLOGY | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | PROGRAM | - |
dc.subject.keywordPlus | SOCIETY | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.relation.journalWebOfScienceCategory | Peripheral Vascular Disease | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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