Role of ginsenosides, the main active components of Panax ginseng, in inflammatory responses and diseases
DC Field | Value | Language |
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dc.contributor.author | Kim, Ji Hye | - |
dc.contributor.author | Yi, Young-Su | - |
dc.contributor.author | Kim, Mi-Yeon | - |
dc.contributor.author | Cho, Jae Youl | - |
dc.date.available | 2018-05-08T14:28:54Z | - |
dc.date.created | 2018-04-17 | - |
dc.date.issued | 2017-10 | - |
dc.identifier.issn | 1226-8453 | - |
dc.identifier.uri | http://scholarworks.bwise.kr/ssu/handle/2018.sw.ssu/6228 | - |
dc.description.abstract | Panax ginseng is one of the most universally used herbal medicines in Asian and Western countries. Most of the biological activities of ginseng are derived from its main constituents, ginsenosides. Interestingly, a number of studies have reported that ginsenosides and their metabolites/derivatives-including ginsenoside (G)-Rb1, compound K, G-Rb2, G-Rd, G-Re, G-Rg1, G-Rg3, G-Rg5, G-Rh1, G-Rh2, and G-Rp1-exert anti-inflammatory activities in inflammatory responses by suppressing the production of proinflammatory cytokines and regulating the activities of inflammatory signaling pathways, such as nuclear factor-kappa B and activator protein-1. This review discusses recent studies regarding molecular mechanisms by which ginsenosides play critical roles in inflammatory responses and diseases, and provides evidence showing their potential to prevent and treat inflammatory diseases. (C) 2017 The Korean Society of Ginseng, Published by Elsevier Korea LLC. | - |
dc.publisher | KOREAN SOC GINSENG | - |
dc.relation.isPartOf | JOURNAL OF GINSENG RESEARCH | - |
dc.subject | NF-KAPPA-B | - |
dc.subject | ISCHEMIA-REPERFUSION INJURY | - |
dc.subject | ADAPTIVE IMMUNE-RESPONSES | - |
dc.subject | METABOLITE COMPOUND K | - |
dc.subject | BONE-MINERAL DENSITY | - |
dc.subject | GLUCOCORTICOID-RECEPTOR | - |
dc.subject | RAW264.7 CELLS | - |
dc.subject | MICROGLIAL ACTIVATION | - |
dc.subject | 20(S)-GINSENOSIDE RH2 | - |
dc.subject | RHEUMATOID-ARTHRITIS | - |
dc.title | Role of ginsenosides, the main active components of Panax ginseng, in inflammatory responses and diseases | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.jgr.2016.08.004 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | JOURNAL OF GINSENG RESEARCH, v.41, no.4, pp.435 - 443 | - |
dc.identifier.kciid | ART002274257 | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000413583900001 | - |
dc.identifier.scopusid | 2-s2.0-84994504341 | - |
dc.citation.endPage | 443 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 435 | - |
dc.citation.title | JOURNAL OF GINSENG RESEARCH | - |
dc.citation.volume | 41 | - |
dc.contributor.affiliatedAuthor | Kim, Mi-Yeon | - |
dc.type.docType | Review | - |
dc.description.oadoiVersion | published | - |
dc.subject.keywordAuthor | ginsenosides | - |
dc.subject.keywordAuthor | inflammation | - |
dc.subject.keywordAuthor | inflammatory diseases | - |
dc.subject.keywordAuthor | Panax ginseng | - |
dc.subject.keywordAuthor | signaling | - |
dc.subject.keywordPlus | NF-KAPPA-B | - |
dc.subject.keywordPlus | ISCHEMIA-REPERFUSION INJURY | - |
dc.subject.keywordPlus | ADAPTIVE IMMUNE-RESPONSES | - |
dc.subject.keywordPlus | METABOLITE COMPOUND K | - |
dc.subject.keywordPlus | BONE-MINERAL DENSITY | - |
dc.subject.keywordPlus | GLUCOCORTICOID-RECEPTOR | - |
dc.subject.keywordPlus | RAW264.7 CELLS | - |
dc.subject.keywordPlus | MICROGLIAL ACTIVATION | - |
dc.subject.keywordPlus | 20(S)-GINSENOSIDE RH2 | - |
dc.subject.keywordPlus | RHEUMATOID-ARTHRITIS | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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