Drug Treatment Protocol for HIV Infected Patients Using State Feedback Integral Control Technique상태궤환 적분제어기법을 이용한 HIV 감염 환자에 대한 약물 치료기법
- Other Titles
- 상태궤환 적분제어기법을 이용한 HIV 감염 환자에 대한 약물 치료기법
- Authors
- 조남훈
- Issue Date
- Oct-2015
- Publisher
- Korean Institute of Electrical Engineers
- Keywords
- HIV infection model; Parameter uncertainties; Integral control; Modelling error
- Citation
- Transactions of the Korean Institute of Electrical Engineers, v.64, no.10, pp.1454 - 1459
- Journal Title
- Transactions of the Korean Institute of Electrical Engineers
- Volume
- 64
- Number
- 10
- Start Page
- 1454
- End Page
- 1459
- URI
- http://scholarworks.bwise.kr/ssu/handle/2018.sw.ssu/9567
- DOI
- 10.5370/KIEE.2015.64.10.1454
- ISSN
- 1975-8359
- Abstract
- In this paper, a drug treatment protocol is proposed for an HIV infection model that explicitly includes the concentration of healthy T cells, infected T cells, and HIV. Since real parameters of HIV infection model differ from patient to patient, most drug treatment protocols are not able to achieve the treatment goal in the presence of modelling errors.
Recently, based on the nonlinear robust control theory, a robust treatment protocol has been proposed that deals with parameter uncertainties. Although the developed scheme is inherently complex, it cannot be applied to the case where all parameters are unknown. In this paper, we propose a new drug treatment protocol that is much simpler than the previous one but can achieve the treatment goal even when all model parameters are unknown. The simulation results verify that the substantial improvement in the performance can be achieved by the proposed scheme.
- Files in This Item
-
Go to Link
- Appears in
Collections - College of Engineering > School of Electrical Engineering > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.