Risk of Hip Fractures in Men with Alpha-Blockers: A Nationwide Study Base on Claim Registry
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 서기현 | - |
dc.contributor.author | 이영균 | - |
dc.contributor.author | 하용찬 | - |
dc.date.available | 2019-03-08T19:59:32Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 2287-6375 | - |
dc.identifier.issn | 2287-7029 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/11173 | - |
dc.description.abstract | Background: Alpha-blocker can result in falling and fractures because of adverse effect such as orthostatic hypotension due to vasodilatory effect. We investigated the association between the alpha-blocker and the risk of osteoporotic hip fractures using a nationwide claim database. Methods: We identified 1,051,651 men 65 years of age or older who had prescription records of alpha-blocker from nationwide medical claim database, from 2007 to 2012. Alpha-blockers were classified as non-specific general (NSG), non-specific slow-release (NSSR), uro-specific general (USG), and uro-specific slow release (USSR). Results: Total of 6,553 hip fractures were observed. The incidences of hip fracture within 1 year were higher than those of the reference periods in all type of alpha-blocker. Hazard ratio peaked at early period of alpha-blocker, and decreased with time, regardless of type of alpha-blocker. Conclusions: Use of alpha-blocker is associated with increased risk of hip fracture, especially in early use. | - |
dc.format.extent | 4 | - |
dc.publisher | 대한골대사학회 | - |
dc.title | Risk of Hip Fractures in Men with Alpha-Blockers: A Nationwide Study Base on Claim Registry | - |
dc.type | Article | - |
dc.identifier.doi | 10.11005/jbm.2015.22.1.29 | - |
dc.identifier.bibliographicCitation | 대한골대사학회지, v.22, no.1, pp 29 - 32 | - |
dc.identifier.kciid | ART001969132 | - |
dc.description.isOpenAccess | Y | - |
dc.citation.endPage | 32 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 29 | - |
dc.citation.title | 대한골대사학회지 | - |
dc.citation.volume | 22 | - |
dc.subject.keywordAuthor | Alpha-blocker | - |
dc.subject.keywordAuthor | Hip fracture | - |
dc.subject.keywordAuthor | Registries | - |
dc.description.journalRegisteredClass | kci | - |
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