Fragile skin microbiomes in megacities are assembled by a predominantly niche-based processopen access
- Authors
- Kim, Hye-Jin; Kim, Hanbyul; Kim, Jin Ju; Myeong, Nu Ri; Kim, Taeyune; Park, Taehun; Kim, Eunjoo; Choi, Ji-yei; Lee, Johnhwan; An, Susun; Sul, Woo Jun
- Issue Date
- Mar-2018
- Publisher
- AMER ASSOC ADVANCEMENT SCIENCE
- Citation
- SCIENCE ADVANCES, v.4, no.3
- Journal Title
- SCIENCE ADVANCES
- Volume
- 4
- Number
- 3
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/1140
- DOI
- 10.1126/sciadv.1701581
- ISSN
- 2375-2548
2375-2548
- Abstract
- Given the higher incidence of skin diseases in more urbanized populations and its association with the skin microbiome, we questioned how the skin microbiome differed depending on the degree of urbanization. Skin microbiomes of 231 healthy subjects in five large cities in China varied mainly with environment and socioeconomic status of the cities in question. The differences among microbiomes could be explained by the predominantly niche-based assembly of microbial communities, which was supported by a dominance test, beta-null deviation, and edge-length abundance distribution. Networks among microbes in larger cities were more fragile, which may contribute to the higher incidence of skin diseases in more urbanized environments. These results suggest that microbial ecological theory can provide a framework for understanding crucial health-associated features of the human microbiome.
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- Appears in
Collections - College of Biotechnology & Natural Resource > Department of Systems Biotechnology > 1. Journal Articles
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