Fabrication of Dual Dye-Doped Silica Nanotube as a Fluorescent Ratiometric pH Sensor
- Authors
- Phuong-Diem Nguyen; Dung Thi Xuan Nguyen; Son, Sang Jun; Min, Junhong
- Issue Date
- Nov-2014
- Publisher
- AMER SCIENTIFIC PUBLISHERS
- Keywords
- Silica Nanotube (SNT); Alumina Template (AAO); Fluorescent Isothiocyanate (FITC); Tetramethyl Rhodamine (TMR); pH Sensitive; Encapsulation
- Citation
- JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, v.14, no.11, pp 8719 - 8723
- Pages
- 5
- Journal Title
- JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
- Volume
- 14
- Number
- 11
- Start Page
- 8719
- End Page
- 8723
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/11647
- DOI
- 10.1166/jnn.2014.9974
- ISSN
- 1533-4880
1533-4899
- Abstract
- This study described a novel fabrication of fluorescence co-encapsulating silica nanotubes (F@SNT) and the further application of the as-synthesized nanostructure as a ratiometric pH sensor in buffer solution. Silica nanotubes (SNTs) embedded anodic alumina oxide (AAO) template was fabricated by sol-gel technique, tetramethyl rhodamine (TMR-the reference dye) was incorporated directly onto silica layer via hydrophobic interaction. Subsequently, fluorescent isothiocyanate (FITC-pH sensitive dye) was encapsulated inside poly-dimethylsiloxane (PDMS) matrix and the FITC-PDMS nanocomposite was doped into the hollow structure of SNT using nano-molding lithography. On removing AAO, free-standing SNTs were obtained and were subsequently applied as a ratiometric pH sensor in phosphate buffer solution. The dual dye-doped SNTs showed excellent fluorescence and a good pH sensing performance from pH 5.2-8.0. The results were distinguishable by the emission spectra and by fluorescent visualization. High photostability, sensitivity, biocompatibility with adjustable sizes make dual dye doped-SNT a promising nanostructure for bioapplications.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of ICT Engineering > School of Integrative Engineering > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.