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Artificial nano-pin as a temporal molecular glue for the targeting of acidic tumor cells
- Authors
- Oh, Nam Muk; Oh, Kyung Taek; Youn, Yu Seok; Lee, Eun Seong
- Issue Date
- Aug-2014
- Publisher
- WILEY-BLACKWELL
- Keywords
- nano-pin; dog bone-shaped; pin-shaped; acidic tumor targeting; photosensitizing drug
- Citation
- POLYMERS FOR ADVANCED TECHNOLOGIES, v.25, no.8, pp 842 - 850
- Pages
- 9
- Journal Title
- POLYMERS FOR ADVANCED TECHNOLOGIES
- Volume
- 25
- Number
- 8
- Start Page
- 842
- End Page
- 850
- ISSN
- 1042-7147
1099-1581
- Abstract
- Highly precise control of molecular structure for developing efficient anticancer drug delivery is challenging. Our method reported herein can satisfy the need for building novel hybrid molecule; this molecule serves as a built-in transformer that changes its molecular configuration from a pin-shaped arrangement to a dog bone-shaped arrangement. This approach led to a significant increase in the efficiency of tumor inhibition. Copyright (C) 2014 John Wiley & Sons, Ltd.
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