Surface Modification of Silk Fibroin Nanofibrous Mat with Dextran for Wound Dressing
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Moo Kon | - |
dc.contributor.author | Kwak, Hyo Won | - |
dc.contributor.author | Kim, Hyung Hwan | - |
dc.contributor.author | Kwon, Tae Rin | - |
dc.contributor.author | Kim, So Young | - |
dc.contributor.author | Kim, Beom Joon | - |
dc.contributor.author | Park, Young Hwan | - |
dc.contributor.author | Lee, Ki Hoon | - |
dc.date.available | 2019-03-08T21:56:50Z | - |
dc.date.issued | 2014-06 | - |
dc.identifier.issn | 1229-9197 | - |
dc.identifier.issn | 1875-0052 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/12196 | - |
dc.description.abstract | In this study, we examined the effects of a dextran-modified silk fibroin nanofibrous mat (D-SFNM) on wound healing. To increase the hydrophilicity of silk fibroin (SF), the SF nanofibrous mat (SFNM) was modified with oxidized dextran. The D-SFNM absorbed water faster than the SFNM, and the swelling ratio was increased by approximately 80 % compared with the SFNM. An in vitro cell (NIH3T3) test revealed that fewer cells attached to the D-SFNM than the SFNM, but the proliferation of cells was not significantly affected by the presence of dextran. An in vivo wound healing test with mice indicated that the D-SFNM resulted in a good wound recovery effect similar to a commercial wound dressing material. The increased hydrophilicity of the D-SFNM might balance the moist environment at the wound site, which improves the wound healing compared with the SFNM. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | KOREAN FIBER SOC | - |
dc.title | Surface Modification of Silk Fibroin Nanofibrous Mat with Dextran for Wound Dressing | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s12221-014-1137-2 | - |
dc.identifier.bibliographicCitation | FIBERS AND POLYMERS, v.15, no.6, pp 1137 - 1145 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000338271400005 | - |
dc.identifier.scopusid | 2-s2.0-84904129787 | - |
dc.citation.endPage | 1145 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1137 | - |
dc.citation.title | FIBERS AND POLYMERS | - |
dc.citation.volume | 15 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Silk fibroin | - |
dc.subject.keywordAuthor | Dextran | - |
dc.subject.keywordAuthor | Wound healing | - |
dc.subject.keywordAuthor | Wound dressing | - |
dc.subject.keywordAuthor | Surface modification | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | PROTEIN ADSORPTION | - |
dc.subject.keywordPlus | DIALDEHYDE | - |
dc.subject.keywordPlus | GELATIN | - |
dc.subject.keywordPlus | FILMS | - |
dc.subject.keywordPlus | SKIN | - |
dc.subject.keywordPlus | REGENERATION | - |
dc.subject.keywordPlus | HYDROGEL | - |
dc.subject.keywordPlus | VIVO | - |
dc.subject.keywordPlus | IMMOBILIZATION | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Polymer Science | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Textiles | - |
dc.relation.journalWebOfScienceCategory | Polymer Science | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.