Carbon-based drug delivery carriers for cancer therapy
- Authors
- Lim, Dong-Jin; Sim, Myeongbu; Oh, Leeseul; Lim, Kyunghee; Park, Hansoo
- Issue Date
- Jan-2014
- Publisher
- PHARMACEUTICAL SOC KOREA
- Keywords
- Nanodiamonds; Graphene oxide; Carbon nanotube; Drug delivery
- Citation
- ARCHIVES OF PHARMACAL RESEARCH, v.37, no.1, pp 43 - 52
- Pages
- 10
- Journal Title
- ARCHIVES OF PHARMACAL RESEARCH
- Volume
- 37
- Number
- 1
- Start Page
- 43
- End Page
- 52
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/12622
- DOI
- 10.1007/s12272-013-0277-1
- ISSN
- 0253-6269
1976-3786
- Abstract
- In the search to improve anticancer therapies, several drug carriers, including carbon-based nanomaterials have been studied. Both liposomes and polymeric microspheres have been used in anticancer drugs. However, there remains an on-going need for better therapeutic materials that have good drug solubility, an ability to reduce systemic toxicity through specific-tumor targeting, and rapid clearance. In this regard, carbon allotropes such as graphene oxide (GOs), carbon nanotubes (CNTs), and nanodiamonds (NDs), have been investigated, as they possess sufficient surface-to-volume ratio, thermal conductivity, rigid structural properties capable of post-chemical modification, and excellent biocompatibility. This review is aimed at exploring these carbon-based nanomaterials for use as multifaceted cancer drug carriers and is intended to demonstrate that GOs, CNTs, and NDs are likely to improve chemotherapeutical strategy for cancers in either a sole or combinational manner.
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Collections - College of Engineering > School of Chemical Engineering and Material Science > 1. Journal Articles
- College of ICT Engineering > School of Integrative Engineering > 1. Journal Articles
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