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Screening of Various Sources of Phytochemicals for Neuroprotective Activity against Oxygen-Glucose Deprivation in vitro
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Chang, Hyun-Joo | - |
| dc.contributor.author | Kim, Young Sup | - |
| dc.contributor.author | Ryu, Shi Yong | - |
| dc.contributor.author | Chun, Hyang Sook | - |
| dc.date.available | 2019-03-09T01:40:19Z | - |
| dc.date.issued | 2013-08 | - |
| dc.identifier.issn | 1738-2203 | - |
| dc.identifier.issn | 2234-344X | - |
| dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/14441 | - |
| dc.description.abstract | Neuroprotective activities of 176 phytochemicals were investigated against oxygen-glucose deprivation in vitro using primary cortical neuron culture. Diterpenes (taxol and taxol C) were the most potent neuroprotective compounds. EC50 of taxol and taxol C were 0.402 and 0.452 mu M, respectively. This result supports the use of an in vitro model as initial screening for neuroprotective candidates, which warrants further testing in animal models. | - |
| dc.format.extent | 5 | - |
| dc.language | 영어 | - |
| dc.language.iso | ENG | - |
| dc.publisher | KOREAN SOC APPLIED BIOLOGICAL CHEMISTRY | - |
| dc.title | Screening of Various Sources of Phytochemicals for Neuroprotective Activity against Oxygen-Glucose Deprivation in vitro | - |
| dc.type | Article | - |
| dc.identifier.doi | 10.1007/s13765-013-3108-7 | - |
| dc.identifier.bibliographicCitation | JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY, v.56, no.4, pp 451 - 455 | - |
| dc.identifier.kciid | ART001794289 | - |
| dc.description.isOpenAccess | N | - |
| dc.identifier.wosid | 000324359100012 | - |
| dc.identifier.scopusid | 2-s2.0-84881562663 | - |
| dc.citation.endPage | 455 | - |
| dc.citation.number | 4 | - |
| dc.citation.startPage | 451 | - |
| dc.citation.title | JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY | - |
| dc.citation.volume | 56 | - |
| dc.type.docType | Article | - |
| dc.publisher.location | 대한민국 | - |
| dc.subject.keywordAuthor | cerebral cortical neuron | - |
| dc.subject.keywordAuthor | ischemia | - |
| dc.subject.keywordAuthor | neuroprotection | - |
| dc.subject.keywordAuthor | oxygen-glucose deprivation | - |
| dc.subject.keywordAuthor | phytochemical | - |
| dc.subject.keywordAuthor | taxol | - |
| dc.subject.keywordPlus | CEREBRAL-ISCHEMIA | - |
| dc.subject.keywordPlus | BRAIN-INJURY | - |
| dc.subject.keywordPlus | STROKE | - |
| dc.subject.keywordPlus | KINASE | - |
| dc.subject.keywordPlus | RATS | - |
| dc.relation.journalResearchArea | Food Science & Technology | - |
| dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.description.journalRegisteredClass | kci | - |
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