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Preparation of Furfuryl-fish gelatin (F-f.gel) cured using visible-light and its application as an anti-adhesion agent
- Authors
- Park, Shin-Hye; Seo, Si-Yoong; Lee, Hyung-Jae; Na, Ha-Na; Lee, Jea-Woo; Woo, Hee-Dong; Son, Tae-Il
- Issue Date
- Aug-2012
- Publisher
- POLYMER SOC KOREA
- Keywords
- fish gelatin; anti-adhesion agent; photo curing; furfuryl group; gelatin film
- Citation
- MACROMOLECULAR RESEARCH, v.20, no.8, pp 842 - 846
- Pages
- 5
- Journal Title
- MACROMOLECULAR RESEARCH
- Volume
- 20
- Number
- 8
- Start Page
- 842
- End Page
- 846
- ISSN
- 1598-5032
2092-7673
- Abstract
- Adhesions occurring on a variety tissues and operation sites are a serious side effect of surgery and may require additional surgery for removal. Therefore, Furfuryl-fish gelatin (F-f.gel) was synthesized by introducing a furan ring to fish gelatin for application as an anti-adhesion agent. F-f.gel was cured by visible-light irradiation, which changed the material from a solution to a film. The prepared F-f.gel was characterized by proton nuclear magnetic resonance spectroscopy (H-1 NMR), substitution ratio, gel permeation chromatography (GPC), methyl thiazolyl tetrazolium (MTT) assay, and tests for measuring photo immobilization, water contact angle (WCA), and cell attachment. The results showed that F-f.gel was effective as an anti-adhesion agent.
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