Application of Sepsis-3 Criteria to Korean Patients with Critical Illnessesopen access
- Authors
- Kim, Jae Yeol; Kim, Hwan Il; Suh, Gee Young; Yoon, Sang Won; Kim, Tae-Yop; Lee, Sang Haak; Moon, Jae Young; Kwon, Jae-Young; Na, Sungwon; Ryu, Ho Geol; Park, Jisook; Koh, Younsuck
- Issue Date
- Feb-2019
- Publisher
- 대한중환자의학회
- Keywords
- intensive care units; organ dysfunction; Sepsis; Sepsis-3; septic shock
- Citation
- Acute and Critical Care, v.34, no.1, pp 30 - 37
- Pages
- 8
- Journal Title
- Acute and Critical Care
- Volume
- 34
- Number
- 1
- Start Page
- 30
- End Page
- 37
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/18427
- DOI
- 10.4266/acc.2018.00318
- ISSN
- 2586-6052
2586-6060
- Abstract
- Background:The 2016 Society of Critical Care Medicine (SCCM)/European Society of Intensive Care Medicine (ESICM) task force for Sepsis-3 devised new definitions for sepsis, sepsis with organ dysfunction and septic shock. Although Sepsis-3 was data-driven, evidence-based approach, East Asian descents comprised minor portions of the project population.
Methods:We selected Korean participants from the fever and antipyretics in critically ill patients evaluation (FACE) study, a joint study between Korea and Japan. We calculated the concordance rates for sepsis diagnosis between Sepsis-2 and Sepsis-3 criteria and evaluated mortality rates of sepsis, sepsis with organ dysfunction, and septic shock by Sepsis-3 criteria using the selected data.
Results:Korean participants of the FACE study were 913 (383 with sepsis and 530 without sepsis by Sepsis-2 criteria). The concordance rate for sepsis diagnosis between Sepsis-2 and Sepsis-3 criteria was 55.4%. The intensive care unit (ICU) and 28-day mortality rates of sepsis, sepsis with organ dysfunction, and septic shock patients according to Sepsis-3 criteria were 26.2% and 31.0%, 27.5% and 32.5%, and 40.8% and 43.4%, respectively. The quick Sequential Organ Failure Assessment (qSOFA) was inferior not only to SOFA but also to systemic inflammatory response syndrome (SIRS) for predicting ICU and 28-day mortality.
Conclusions:The concordance rates for sepsis diagnosis between Sepsis-2 and Sepsis-3 criteria were low. Mortality rate for septic shock in Koreans was consistent with estimates made by the 2016 SCCM/ESICM task force. SOFA and SIRS were better than qSOFA for predicting ICU and 28-day mortality in Korean ICU patients.
- Files in This Item
-
- Appears in
Collections - ETC > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/18427)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.