Two new hemiterpene glycosides from the leaves of Ilex rotunda. thunb
- Authors
- Kim, Manh Heun; Park, Kwan Hee; Oh, Myeong Hwan; Kim, Han Hyuk; Choe, Kang In; Park, Sang Hee; Lee, Min Won
- Issue Date
- Oct-2012
- Publisher
- PHARMACEUTICAL SOC KOREA
- Keywords
- Ilex rotunda; Hemiterpenes; Caffeoylquinic acids; Anti-oxidative activity
- Citation
- ARCHIVES OF PHARMACAL RESEARCH, v.35, no.10, pp 1779 - 1784
- Pages
- 6
- Journal Title
- ARCHIVES OF PHARMACAL RESEARCH
- Volume
- 35
- Number
- 10
- Start Page
- 1779
- End Page
- 1784
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/20144
- DOI
- 10.1007/s12272-012-1010-1
- ISSN
- 0253-6269
- Abstract
- Chromatographic separation of the 80% MeOH extract of the leaves of Ilex rotunda (IR) led to isolation of two new hemiterpene glycosides, tentatively named as rotundarpenoside A (1) and rotundarpenoside B (2), along with five known caffeoyl derivatives (3-7). The chemical structures of these compounds were elucidated using 1D/2D NMR, HR-MS, and the absolute configuration was confirmed by Mosher's method. In order to evaluate their anti-oxidative activities, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and xanthine oxidase superoxide scavenging activities (NBT) were determined.
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Collections - College of Pharmacy > School of Pharmacy > 1. Journal Articles
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