Genomic characterization of a cell-culture-adapted Korean human G9P[8] rotavirus, CAU05-202
- Authors
- Shin, Jong Wook; Van Phan Le; Van Thai Than; Lim, Inseok; Yoon, Yoosik; Kim, Kijeong; Chung, Sang-In; Myung, Soon Chul; Kim, Wonyong
- Issue Date
- Apr-2012
- Publisher
- SPRINGER WIEN
- Citation
- ARCHIVES OF VIROLOGY, v.157, no.4, pp 753 - 759
- Pages
- 7
- Journal Title
- ARCHIVES OF VIROLOGY
- Volume
- 157
- Number
- 4
- Start Page
- 753
- End Page
- 759
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/20428
- DOI
- 10.1007/s00705-012-1232-z
- ISSN
- 0304-8608
1432-8798
- Abstract
- The human rotavirus G9 strain is the fifth most common rotavirus worldwide. A human rotavirus G9P[8] strain CAU05-202 was isolated from a young child with diarrhea using a cell culture system, and its major gene sequences were determined. Phylogenetic analysis of the VP7 gene revealed that CAU05-202 clustered into genetic lineage III-d and was most closely related to G9 rotaviruses from Turkey (strain GUH13) and Sri Lanka (strain 05SLC056 and 05SLC057). VP4 and NSP4 gene analysis showed that CAU05-202 belongs to the P[8]-3 lineage and genotype B, respectively. In addition, CAU05-202 has a long RNA electropherotype, supported by VP6 gene analysis, which is clearly associated with subgroup II specificity. Analysis of the G9 rotavirus strain CAU05-202 provides information concerning the genetic relationships among global rotavirus G9 strains, suggesting that closely related G9 strains are persistent and widespread in Asian countries.
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