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Sesquiterpenes and Other Constituents from Dendranthema zawadskii var. latilobum

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dc.contributor.authorShin, Hyun Jung-
dc.contributor.authorLee, So Young-
dc.contributor.authorKim, Ju Sun-
dc.contributor.authorLee, Sanghyun-
dc.contributor.authorChoi, Ran Joo-
dc.contributor.authorChung, Ha Sook-
dc.contributor.authorKim, Yeong Shik-
dc.contributor.authorKang, Sam Sik-
dc.date.available2019-05-29T07:39:46Z-
dc.date.issued2012-03-
dc.identifier.issn0009-2363-
dc.identifier.issn1347-5223-
dc.identifier.urihttps://scholarworks.bwise.kr/cau/handle/2019.sw.cau/20462-
dc.description.abstractSix new germacranolides, zawadskinolides A-F (1-6), and a new eudesmane glucoside, chrysantiloboside (7) were isolated from the aerial parts of Dendranthema zawadskii var. latilobum, along with thirteen known constituents. Their structures were elucidated by means of spectroscopic evidence. Bioassay showed that flavonoids such as apigenin (9), (-)-eriodictyol (10) and nepetin (12), as well as the sesquiterpene lactone, zawadskinolide F (6), inhibited nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells with IC50 values of 66.15, 132.55, 35.44, and 91.32 mu m, respectively.-
dc.format.extent9-
dc.language영어-
dc.language.isoENG-
dc.publisherPHARMACEUTICAL SOC JAPAN-
dc.titleSesquiterpenes and Other Constituents from Dendranthema zawadskii var. latilobum-
dc.typeArticle-
dc.identifier.doi10.1248/cpb.60.306-
dc.identifier.bibliographicCitationCHEMICAL & PHARMACEUTICAL BULLETIN, v.60, no.3, pp 306 - 314-
dc.description.isOpenAccessN-
dc.identifier.wosid000300923400003-
dc.identifier.scopusid2-s2.0-84863272714-
dc.citation.endPage314-
dc.citation.number3-
dc.citation.startPage306-
dc.citation.titleCHEMICAL & PHARMACEUTICAL BULLETIN-
dc.citation.volume60-
dc.type.docTypeArticle-
dc.publisher.location일본-
dc.subject.keywordAuthorDendranthema zawadskii var. latilobum-
dc.subject.keywordAuthorAsteraceae-
dc.subject.keywordAuthorgermacranolide-
dc.subject.keywordAuthoreudesmane glucoside-
dc.subject.keywordAuthornitric oxide inhibition-
dc.subject.keywordPlusANTIINFLAMMATORY ACTIVITY-
dc.subject.keywordPlusSTRUCTURAL ELUCIDATION-
dc.subject.keywordPlusTUMOR INHIBITORS-
dc.subject.keywordPlusLACTONES-
dc.subject.keywordPlusGERMACRANOLIDE-
dc.subject.keywordPlusCOMPOSITAE-
dc.subject.keywordPlusGLYCOSIDES-
dc.subject.keywordPlusARTEMISIA-
dc.subject.keywordPlusAJANOLIDE-
dc.subject.keywordPlusLINARIN-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.relation.journalWebOfScienceCategoryPharmacology & Pharmacy-
dc.description.journalRegisteredClasssci-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
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