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Antioxidant activity of the methanolic extract of the newly generated vegetable, baemuchae (xBrassicoraphanus)
- Authors
- Mok, So-Youn; Choi, Mi Jin; Kim, Jongkee; Cho, Eun Ju; Lee, Sanghyun
- Issue Date
- Mar-2012
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Keywords
- Antioxidant activity; Baemuchae (xBrassicoraphanus); Ferulic acid; Radical scavenging effect
- Citation
- FOOD AND CHEMICAL TOXICOLOGY, v.50, no.3-4, pp 848 - 853
- Pages
- 6
- Journal Title
- FOOD AND CHEMICAL TOXICOLOGY
- Volume
- 50
- Number
- 3-4
- Start Page
- 848
- End Page
- 853
- ISSN
- 0278-6915
1873-6351
- Abstract
- We investigated the radical scavenging activity and protective effects of the methanol extract (ME) and ferulic acid (FA) from baemuchae (xBrassicoraphanus) against oxidative stress in vitro and on a cellular system using LLC-PK1 renal epithelial cells. In vitro, ME and FA showed dose-dependent radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl and hydroxyl radicals. LLC-PK1 cells displayed decreased viability in response to nitric oxide-induced oxidative stress. However. ME and FA significantly increased LLC-PK1 cell viability in a dose-dependent manner. Based on HPLC/UV analysis, the FA content was higher in the shoot of baemuchae than in the root. The results of the present study suggest that baemuchae may be a promising source of antioxidants against oxidative stress induced by free radicals. (C) 2012 Elsevier Ltd. All rights reserved.
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