Antibacterial Activity of Triterpenoids from Clerodendron trichotomum
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ji Won Choi | - |
dc.contributor.author | 조은주 | - |
dc.contributor.author | Dong Gu Lee | - |
dc.contributor.author | 최경 | - |
dc.contributor.author | Jajung Ku | - |
dc.contributor.author | Kwang-Woo Park | - |
dc.contributor.author | 이상현 | - |
dc.date.available | 2019-05-29T09:13:12Z | - |
dc.date.issued | 2012-09 | - |
dc.identifier.issn | 1976-0442 | - |
dc.identifier.issn | 2234-7941 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/20668 | - |
dc.description.abstract | The aim of this research was to investigate the antibacterial activity of Clerodendron trichotomum. Antibacterial activities of the n-hexane, methylene chloride (MC), ethyl acetate,and n-butanol fractions from C. trichotomum were tested against Staphylococcus aureus, Escherichia coli, and Helicobacter pylori. The n-hexane and MC fractions showed antibacterial activity against H. pylori at a concentration of 1.7 mg/mL and showed inhibition zones of 10 and 11 mm in disc assay, respectively. Further testing of 22-dehydroclerosterol and β-amyrin (each 3.4mg/mL) from the MC fraction of C. trichotomum revealed moderate antibacterial effects against E. coli, S. aureus, and H. pylori. In particular, β-amyrin showed clear zones of 12 and 13mm against E. coli and H. pylori, respectively, suggesting its potential as an antibacterial agent. The active compounds from C. trichotomum might provide a promising therapeutic agent against infections by E. coli, S. aureus, and H. pylori. | - |
dc.format.extent | 4 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 한국응용생명화학회 | - |
dc.title | Antibacterial Activity of Triterpenoids from Clerodendron trichotomum | - |
dc.type | Article | - |
dc.identifier.bibliographicCitation | Journal of Applied Biological Chemistry, v.55, no.3, pp 169 - 172 | - |
dc.identifier.kciid | ART001700348 | - |
dc.description.isOpenAccess | N | - |
dc.citation.endPage | 172 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 169 | - |
dc.citation.title | Journal of Applied Biological Chemistry | - |
dc.citation.volume | 55 | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | antibacterial activity | - |
dc.subject.keywordAuthor | β-amyrin | - |
dc.subject.keywordAuthor | Clerodendron trichotomum | - |
dc.subject.keywordAuthor | 22-dehydroclerosterol | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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