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Extremely low frequency magnetic field induces oxidative stress in mouse cerebellum
- Authors
- Chu, Li Y.; Lee, Jong H.; Nam, Yun S.; Lee, Yu J.; Park, Won-Hee; Lee, Byung-Cheon; Kim, Daejin; Chung, Yoon H.; Jeong, Ji H.
- Issue Date
- Dec-2011
- Publisher
- GENERAL PHYSIOL AND BIOPHYSICS
- Keywords
- Extremely low frequency magnetic field; Lipid peroxidation; Hydroxyl radical; Superoxide dismutase; Ascorbic acid
- Citation
- GENERAL PHYSIOLOGY AND BIOPHYSICS, v.30, no.4, pp 415 - 421
- Pages
- 7
- Journal Title
- GENERAL PHYSIOLOGY AND BIOPHYSICS
- Volume
- 30
- Number
- 4
- Start Page
- 415
- End Page
- 421
- ISSN
- 0231-5882
- Abstract
- We have investigated whether extremely low frequency magnetic field (ELF-MF) induces lipid peroxidation and reactive oxygen species in mouse cerebellum. After exposure to 60 Hz ELF-MF at 2.3 mT intensity for 3 hours, there was a significant increase in malondialdehyde level and hydroxyl radical. ELF-MF significantly induced concomitant increase in superoxide dismutase without alteration in glutathione peroxidase activity. While glutathione contents were not altered, ascorbic acid levels were significantly decreased by ELF-MF exposure. These results indicate that ELF-MF may induce oxidative stress in mouse cerebellum. However, the mechanism remains further to be characterized.
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