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Expression of mucins on the mucosal surface of lungs of 4-week-old pigs
- Authors
- Kim, Chung Hyun; Lee, Kichan; Han, Kiwon; Oh, Yeonsu; Kim, Duyeol; Seo, Hwi Won; Park, Changhoon; Ha, Mi-Kyoung; Kim, Sung-Hoon; Cho, Kyung-Dong; Lee, Bog-Hieu; Chae, Chanhee
- Issue Date
- Apr-2011
- Publisher
- SPRINGER
- Keywords
- Lung; Mucin; Swine
- Citation
- VETERINARY RESEARCH COMMUNICATIONS, v.35, no.4, pp 255 - 260
- Pages
- 6
- Journal Title
- VETERINARY RESEARCH COMMUNICATIONS
- Volume
- 35
- Number
- 4
- Start Page
- 255
- End Page
- 260
- ISSN
- 0165-7380
1573-7446
- Abstract
- The aim of this study was to determine the immunoreactivity of normal small bronchial, bronchiolar, respiratory bronchiolar, and interalveolar epithelium using antibodies to six mucins: MUC1, MUC2, MUC4, MUC5AC, MUC5B, and MUC6. The large, gel-forming secreted mucins MUC2, MUC5AC, and MUC5B were widely expressed in the lower respiratory tract. The results of this study demonstrate that these secreted mucins form a gel to cover and protect the mucosal surface in the lower respiratory tract of pigs.
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