Initial laboratory predictors of severe hepatitis and acute kidney injury in patients with acute hepatitis A
DC Field | Value | Language |
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dc.contributor.author | Cho, Sun Young | - |
dc.contributor.author | Choi, Seong-Ho | - |
dc.contributor.author | Park, Ji-Hoon | - |
dc.contributor.author | Chung, Jin-Won | - |
dc.date.available | 2019-05-29T13:36:59Z | - |
dc.date.issued | 2011-04 | - |
dc.identifier.issn | 0732-8893 | - |
dc.identifier.issn | 1879-0070 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/21624 | - |
dc.description.abstract | The number of adult patients with acute hepatitis A (AH-A) has markedly increased during the last 10 years in Korea. Of special note, an increase in severe complications of AH-A, such as severe liver dysfunction and acute kidney injury (AKI), has emerged as a significant problem. The objective of this study was to identify the initial predictors for development of severe AH-A and AKI in AH-A. We retrospectively reviewed the medical records of 194 patients with AH-A from January 2007 to March 2009. Severe AH-A and AKI developed in 16 (9.3%) and 11(6.4%) patients, respectively. Independent predictors for severe AH-A were low albumin [odds ratio (OR), 10.91; 95% confidence interval (CI), 2.324-51.215; P = 0.002], low total cholesterol (OR, 5.54; 95% Cl, 1.389-22.113; P = 0.015), and elevated alanine aminotransferase (OR, 20.87; 95% Cl, 4.581-95.067; P < 0.001). Also, high level of C-reactive protein was independently associated with AKI occurrence in AH-A (OR, 10.91; 95% Cl, 2.324-51.215; P = 0.002). (C) 2011 Elsevier Inc. All rights reserved. | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.title | Initial laboratory predictors of severe hepatitis and acute kidney injury in patients with acute hepatitis A | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.diagmicrobio.2010.10.015 | - |
dc.identifier.bibliographicCitation | DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, v.69, no.4, pp 400 - 404 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000288819700008 | - |
dc.identifier.scopusid | 2-s2.0-79952412502 | - |
dc.citation.endPage | 404 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 400 | - |
dc.citation.title | DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | - |
dc.citation.volume | 69 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | Hepatitis A | - |
dc.subject.keywordAuthor | Severe hepatitis A | - |
dc.subject.keywordAuthor | Acute kidney injury | - |
dc.subject.keywordPlus | ACUTE-RENAL-FAILURE | - |
dc.subject.keywordPlus | FULMINANT-HEPATITIS | - |
dc.subject.keywordPlus | THROMBOCYTOPENIA | - |
dc.subject.keywordPlus | INFECTION | - |
dc.subject.keywordPlus | JAUNDICE | - |
dc.subject.keywordPlus | ADULTS | - |
dc.relation.journalResearchArea | Infectious Diseases | - |
dc.relation.journalResearchArea | Microbiology | - |
dc.relation.journalWebOfScienceCategory | Infectious Diseases | - |
dc.relation.journalWebOfScienceCategory | Microbiology | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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