Effect of Oral Administration of Korean Red Ginseng on Influenza A (H1N1) Virus Infection
DC Field | Value | Language |
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dc.contributor.author | Kim, Jin Young | - |
dc.contributor.author | Kim, Hyoung Jin | - |
dc.contributor.author | Kim, Hong-Jin | - |
dc.date.available | 2019-05-29T13:39:38Z | - |
dc.date.issued | 2011-03 | - |
dc.identifier.issn | 1226-8453 | - |
dc.identifier.issn | 2093-4947 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/21712 | - |
dc.description.abstract | Korean red ginseng (RG), which is a ginseng treated by heating and steaming, has biological activity similar to Panax ginseng. The effect of ginseng on influenza infection has not been studied although it is known to have a broad range of biological activities. The aim of the study is to investigate the effect of RG extract on influenza A (H1N1) virus infection. We investigated the inhibitory effect of RG extract on plaque formation by influenza A virus in a cell-based plaque assay, and the effect of orally administered RG on influenza A virus infection in mice. RG extract, which was applied at a non-cytotoxic concentration, inhibited plaque formation by influenza A virus in the cell-based plaque assay. The orally administered RG extract ameliorated body weight loss and significantly increased survival in mice infected with influenza A virus. Our results suggest that RG extract has components that reduce the severity of infection by influenza A virus and could potentially be used as a complement to treatment of influenza A virus infections. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | KOREAN SOC GINSENG | - |
dc.title | Effect of Oral Administration of Korean Red Ginseng on Influenza A (H1N1) Virus Infection | - |
dc.type | Article | - |
dc.identifier.doi | 10.5142/jgr.2011.35.1.104 | - |
dc.identifier.bibliographicCitation | JOURNAL OF GINSENG RESEARCH, v.35, no.1, pp 104 - 110 | - |
dc.identifier.kciid | ART001541698 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000288935700013 | - |
dc.identifier.scopusid | 2-s2.0-79955572015 | - |
dc.citation.endPage | 110 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 104 | - |
dc.citation.title | JOURNAL OF GINSENG RESEARCH | - |
dc.citation.volume | 35 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Panax ginseng | - |
dc.subject.keywordAuthor | Korean red ginseng | - |
dc.subject.keywordAuthor | Influenza A virus | - |
dc.subject.keywordAuthor | Oseltamivir | - |
dc.subject.keywordPlus | IMMUNE-RESPONSE | - |
dc.subject.keywordPlus | PANAX-GINSENG | - |
dc.subject.keywordPlus | MICE | - |
dc.subject.keywordPlus | EXTRACT | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | INHIBITION | - |
dc.subject.keywordPlus | EFFICACY | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | ASSAY | - |
dc.relation.journalResearchArea | Plant Sciences | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalResearchArea | Integrative & Complementary Medicine | - |
dc.relation.journalWebOfScienceCategory | Plant Sciences | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Integrative & Complementary Medicine | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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