Effect of Oral Administration of Korean Red Ginseng on Influenza A (H1N1) Virus Infection
- Authors
- Kim, Jin Young; Kim, Hyoung Jin; Kim, Hong-Jin
- Issue Date
- Mar-2011
- Publisher
- KOREAN SOC GINSENG
- Keywords
- Panax ginseng; Korean red ginseng; Influenza A virus; Oseltamivir
- Citation
- JOURNAL OF GINSENG RESEARCH, v.35, no.1, pp 104 - 110
- Pages
- 7
- Journal Title
- JOURNAL OF GINSENG RESEARCH
- Volume
- 35
- Number
- 1
- Start Page
- 104
- End Page
- 110
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/21712
- DOI
- 10.5142/jgr.2011.35.1.104
- ISSN
- 1226-8453
2093-4947
- Abstract
- Korean red ginseng (RG), which is a ginseng treated by heating and steaming, has biological activity similar to Panax ginseng. The effect of ginseng on influenza infection has not been studied although it is known to have a broad range of biological activities. The aim of the study is to investigate the effect of RG extract on influenza A (H1N1) virus infection. We investigated the inhibitory effect of RG extract on plaque formation by influenza A virus in a cell-based plaque assay, and the effect of orally administered RG on influenza A virus infection in mice. RG extract, which was applied at a non-cytotoxic concentration, inhibited plaque formation by influenza A virus in the cell-based plaque assay. The orally administered RG extract ameliorated body weight loss and significantly increased survival in mice infected with influenza A virus. Our results suggest that RG extract has components that reduce the severity of infection by influenza A virus and could potentially be used as a complement to treatment of influenza A virus infections.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Pharmacy > School of Pharmacy > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/21712)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.