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Polyoxygenated ergostane-type sterols from the liquid culture of Ganoderma applanatum
- Authors
- Lee, So Young; Kim, Ju Sun; Lee, Sanghyun; Kang, Sam Sik
- Issue Date
- 2011
- Publisher
- TAYLOR & FRANCIS LTD
- Keywords
- Ganoderma applanatum; Polyporaceae; polyoxygenated ergostane; 3 beta,5 alpha,6 beta,8 beta,14 alpha-pentahydroxy-(22E,24R)-ergost-22-en-7-one; liquid culture
- Citation
- NATURAL PRODUCT RESEARCH, v.25, no.14, pp 1304 - 1311
- Pages
- 8
- Journal Title
- NATURAL PRODUCT RESEARCH
- Volume
- 25
- Number
- 14
- Start Page
- 1304
- End Page
- 1311
- ISSN
- 1478-6419
1478-6427
- Abstract
- A new polyoxygenated ergostane-type sterol, 3 beta,5 alpha,6 beta,8 beta,14 alpha-pentahydroxy-(22E,24R)-ergost-22-en-7-one (1), has been isolated from the liquid culture of the basidiomycete Ganoderma applanatum together with four known sterols, 3 beta,5 alpha,9 alpha-trihydroxy-(22E,24R)-ergosta-7,22-dien-6-one (2), ergosterol peroxide (3), 6-dehydrocerevisterol (4) and cerevisterol (5). Two of these sterols (2, 4) are reported to have been isolated from this species for the first time. The structures of these compounds were determined by chemical and spectroscopic analyses, including 1D- and 2D-NMR, as well as by comparison of their spectroscopic data with those reported in the literature.
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