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A facile and sensitive immunoassay for the detection of alpha-fetoprotein using gold-coated magnetic nanoparticle clusters and dynamic light scattering
- Authors
- Chun, Changho; Joo, Jinmyoung; Kwon, Donghoon; Kim, Chang Sup; Cha, Hyung Joon; Chung, Myung-Sub; Jeon, Sangmin
- Issue Date
- 21-Oct-2011
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- CHEMICAL COMMUNICATIONS, v.47, no.39, pp 11047 - 11049
- Pages
- 3
- Journal Title
- CHEMICAL COMMUNICATIONS
- Volume
- 47
- Number
- 39
- Start Page
- 11047
- End Page
- 11049
- ISSN
- 1359-7345
- Abstract
- A facile and sensitive immunoassay protocol for the detection of alpha-fetoprotein (AFP) was developed using gold-coated iron oxide magnetic nanoclusters and dynamic light scattering (DLS) methods. The increase in the average particle size due to AFP-mediated aggregation was measured using DLS, and the detection limit was better than 0.01 ng mL(-1).
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