Simultaneous GC-MS Analysis of Melatonin and Its Precursors as Ethoxycarbonyl/Pentafluoropropionyl Derivatives in Rat Urine
DC Field | Value | Language |
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dc.contributor.author | Paik, M. J. | - |
dc.contributor.author | Nguyen, D. T. | - |
dc.contributor.author | Kim, Y. J. | - |
dc.contributor.author | Shin, J. Y. | - |
dc.contributor.author | Shim, W. | - |
dc.contributor.author | Cho, E. Y. | - |
dc.contributor.author | Yoon, J. H. | - |
dc.contributor.author | Kim, K. R. | - |
dc.contributor.author | Lee, Y. S. | - |
dc.contributor.author | Kim, N. | - |
dc.contributor.author | Park, S. W. | - |
dc.contributor.author | Lee, G. | - |
dc.contributor.author | Ahn, Y. H. | - |
dc.date.available | 2019-05-30T00:39:05Z | - |
dc.date.issued | 2010-12 | - |
dc.identifier.issn | 0009-5893 | - |
dc.identifier.issn | 1612-1112 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/22056 | - |
dc.description.abstract | Melatonin is synthesized from acetylserotonin, which is a deacetylated product of serotoinin. Simultaneous analysis of melatonin and its precursors in rat urine was performed using their (N,O)-ethoxycarbonyl/N-pentafluoropropionyl (EOC/PFP) derivatives by gas chromatography-mass spectrometry (GC-MS). The mass spectral data of acetylserotonin as mono-O-EOC/mono-N-PFP and serotonin as di-(N,O)-EOC/di-N-PFP derivatives were newly established. This method exhibited good linearity (r >= 0.996), repeatability (% relative standard deviation = 6.9-9.4), accuracy (% relative error = -8.9 to 8.6) with detection limits of 0.005 to 0.03 ng mL(-1). This method was developed for the simultaneous measurement of melatonin and its precursors in rat urine. | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | SPRINGER HEIDELBERG | - |
dc.title | Simultaneous GC-MS Analysis of Melatonin and Its Precursors as Ethoxycarbonyl/Pentafluoropropionyl Derivatives in Rat Urine | - |
dc.type | Article | - |
dc.identifier.doi | 10.1365/s10337-010-1771-y | - |
dc.identifier.bibliographicCitation | CHROMATOGRAPHIA, v.72, no.11-12, pp 1213 - 1217 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000285099500028 | - |
dc.identifier.scopusid | 2-s2.0-78651303868 | - |
dc.citation.endPage | 1217 | - |
dc.citation.number | 11-12 | - |
dc.citation.startPage | 1213 | - |
dc.citation.title | CHROMATOGRAPHIA | - |
dc.citation.volume | 72 | - |
dc.type.docType | Article | - |
dc.publisher.location | 독일 | - |
dc.subject.keywordAuthor | Gas chromatography-mass spectrometry | - |
dc.subject.keywordAuthor | Ethoxycarbonyl/pentafluoropropionyl derivatives | - |
dc.subject.keywordAuthor | Melatonin, acetylserotonin and serotonin | - |
dc.subject.keywordPlus | CHROMATOGRAPHY-MASS SPECTROMETRY | - |
dc.subject.keywordPlus | GAS-CHROMATOGRAPHY | - |
dc.subject.keywordPlus | SEROTONIN | - |
dc.subject.keywordPlus | FORMULATIONS | - |
dc.subject.keywordPlus | METABOLITES | - |
dc.subject.keywordPlus | PINEAL | - |
dc.subject.keywordPlus | PLASMA | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Biochemical Research Methods | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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