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Three New Stereoisomers of Condensed Tannins from the Roots of Rosa multiflora
- Issue Date
- Sep-2010
- Publisher
- PHARMACEUTICAL SOC JAPAN
- Keywords
- Rosa multiflora; condensed tannin; proguibourtinidin; profisetinidin; phlobatannin
- Citation
- CHEMICAL & PHARMACEUTICAL BULLETIN, v.58, no.9, pp 1227 - 1231
- Pages
- 5
- Journal Title
- CHEMICAL & PHARMACEUTICAL BULLETIN
- Volume
- 58
- Number
- 9
- Start Page
- 1227
- End Page
- 1231
- ISSN
- 0009-2363
1347-5223
- Abstract
- Three new stereoisomers of condensed tannins (1-3), and four known phenolic compounds (4-7) were isolated from the 80% acetone extract of the roots of Rosa multiflora Thunberg. The structures of these compounds were elucidated using 1D/2D NMR, high resolution (HR)-MS, and circular dichroism (CD) spectra. In order to evaluate their anti-oxidative and anti-inflammatory activities, their 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and inhibitory activity on nitric oxide (NO) production were determined.
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