Intraperitoneal Ropivacaine Instillation for Postoperative Pain Relief after Laparoscopic Cholecystectomy
- Authors
- Kim, Tae Han; Kang, Hyun; Park, Jun Seok; Chang, In Taik; Park, Sun Gyoo
- Issue Date
- Aug-2010
- Publisher
- KOREAN SURGICAL SOCIETY
- Keywords
- Instillation; Laparoscopic cholecystectomy; Ropivacaine hydrochloride
- Citation
- JOURNAL OF THE KOREAN SURGICAL SOCIETY, v.79, no.2, pp 130 - 136
- Pages
- 7
- Journal Title
- JOURNAL OF THE KOREAN SURGICAL SOCIETY
- Volume
- 79
- Number
- 2
- Start Page
- 130
- End Page
- 136
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/22281
- DOI
- 10.4174/jkss.2010.79.2.130
- ISSN
- 2233-7903
2288--679
- Abstract
- Purpose: A study was designed to assess the effect of intraperitoneal instillation of ropivacaine in larparoscopic cholecystectomy patients using computerized patient controlled anesthesia (PCA). Methods: From January 2009 to June 2009, 40 patients with uncomplicated, symptomatic cholecystitis with cholelithiasis who were referred to Chung-Ang University Medical Center for laparoscopic cholecystectomy were included in the study. Patients in group C (control group) received normal saline 100 ml and those in group I (instillation group) received intraperitoneal instillation of 2 mg/kg of ropivacaine diluted in 100 ml saline at the initiation of pneumoperitoneum. Patients were assessed for pain by blinded investigators at 6 time intervals after surgery; 2 hr, 4 hr, 8 hr, 12 hr, 24 hr, and 48 hr. The frequency at which patients pushed the button of the PCA on bolus requirement (FPB) was assessed by a patient-controlled module on the PCA machine. Results: The mean total fentanyl consumption was lower in group 1 (367.39 +/- 85.88) than in group C (535 +/- 100.29) during the 48 hours (P<0.001). Fentanyl velocity and FPB showed significant difference between the groups (P<0.005). Visual analogue scale (VAS) measured pain scores were significantly lower in group I than in group C at 4 hr (P=0.027), 8 hr (P=0.010), 12 hr (P=0.011). Conclusion: Intraperitoneal instillation of ropivacaine at the beginning of laparoscopic cholecystectomy (LC) combined with normal saline infusion is an effective method for reducing pain after LC. (J. Korean Surg Soc 2010;79:130-136)
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